La vitamine D chez l’adulte : recommandations du GRIO

Benhamou,; Souberbielle,; Cortet,; Fardellone,

doi:10.1016/j.lpm.2011.04.001

Cited by 75 publications

(4 citation statements)

References 66 publications

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“…Serum 25(OH)D determination was performed using an electrochemiluminescence (Cobas E411 immunoassay analyzer, Sterifil, casablaca, Morocco) measuring a range of 3–100 ng/mL or 7.5–250 nmol/L. Based on the thresholds of 25(OH)D levels proposed by the Research Group on Information on Osteoporosis (GRIO) and adopted by the Moroccan Society of Rheumatology to define a vitamin D deficiency or insufficiency, women were classified as sufficient (>30 ng/mL), insufficient (10 to 29.9 ng/mL), and deficient (<10 ng/mL) [ 80 , 81 ].…”

Section: Methodsmentioning

confidence: 99%

Sun Exposure Score and Vitamin D Levels in Moroccan Women of Childbearing Age

et al. 2023

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Sunlight exposure is an essential source of vitamin D for many humans. However, hypovitaminosis D is a global public health problem. This study aimed to develop and validate a sun exposure score (SES) and correlate it with serum 25-hydroxyvitamin D levels in women of childbearing age. One hundred and sixty women aged 18 to 45 years residing in Meknes, Morocco, were included. A questionnaire estimating the sun exposure score and blood analysis of serum 25-OHD concentration were performed. The questionnaire’s reliability and construct validity were evaluated using Cronbach’s alpha and factor analysis. Spearman’s test was used to assess the correlation between SES and 25-OHD levels. The score’s reliability and construct validity were good, with Cronbach’s alpha values >0.70 and factorial saturation ranging from 0.696 to 0.948. Serum 25-OHD levels were significantly associated with the total sun exposure score, and all SES domains (Rho was 0.615 (p < 0.0001), 0.307 (p < 0.0001), 0.605 (p < 0.0001), and 0.424 (p < 0.0001) for total SES, indoor exposure domain, outdoor exposure domain, and sun protection practice domain, respectively). In addition, median 25-OHD levels increased significantly when sun exposure was changed from insufficient to sufficient (p < 0.0001). The results suggest that the sun exposure score could be used as a clinical tool to assess vitamin D levels in women of childbearing age.

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Section: Methodsmentioning

confidence: 99%

Sun Exposure Score and Vitamin D Levels in Moroccan Women of Childbearing Age

et al. 2023

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“…The status of vitamin D was evaluated by serum 25(OH)D concentrations measurement and classified as per French ORIG guidelines (deficient: <25 nmol/L (<10 µ g/L), insufficient: 25-75 nmol/L (10-30 µg/L) and sufficient: ≥75 nmol/L (≥30 µg/L)) [21,27]. Two different time points were selected: (i) up to three months before the SARS-CoV-2 infection onset (T1), and (ii) during the first week of hospitalisation (T2).…”

Section: Serum Concentrations Of 25(oh)d and Vitamin D Statusmentioning

confidence: 99%

“…Moreover, the analysis of an elderly or even very elderly population, which is rarely represented in the literature, also makes our work interesting. To our knowledge, only one study has looked at the impact of pre-hospitalization supplementation in the very elderly [27]. As previously mentioned, the population of our study is representative of patients hospitalised for COVID-19 and of patients presenting severe forms of the disease during the first wave of the COVID-19 pandemic.…”

Section: Limitations and Strengths Of The Studymentioning

confidence: 99%

Vitamin D and COVID-19 Severity in Hospitalized Older Patients: Potential Benefit of Prehospital Vitamin D Supplementation

et al. 2022

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Studies involving the associations between vitamin D supplementation taken before the onset of COVID-19 infection and the clinical outcomes are still scarce and this issue remains controversial. This study aimed to assess the relationships between vitamin D (VitD) status and supplementation and coronavirus disease 2019 (COVID-19) severity in older adults (average age of 78 years) hospitalized for COVID-19. We conducted an observational retrospective cohort study with 228 older hospitalized patients during the first wave of the COVID-19 pandemic. The outcomes were in-hospital mortality secondary to COVID-19 or critically severe COVID-19. A logistic regression analysis was conducted to test whether pre-hospital VitD supplementation was independently associated with severity. In this study, 46% of patients developed a severe form and the overall in-hospital mortality was 15%. Sixty-six (29%) patients received a VitD supplement during the 3 months preceding the infection onset. Additionally, a VitD supplement was associated with fewer severe COVID-19 forms (OR = 0.426, p = 0.0135) and intensive care unit (ICU) admissions (OR = 0.341, p = 0.0076). As expected, age > 70 years, male gender and BMI ≥ 35 kg/m2 were independent risk factors for severe forms of COVID-19. No relationship between serum 25(OH)D levels and the severity of the COVID-19 was identified. VitD supplementation taken during the 3 months preceding the infection onset may have a protective effect on the development of severe COVID-19 forms in older adults. Randomized controlled trials and large-scale cohort studies are necessary to strengthen this observation.

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“…Vitamin D deficiency affects more than one billion people at all stages of life worldwide [6]. It occurs most in the elderly, smokers, obese individuals and patients with chronic diseases such as diabetes mellitus, hypertension, and various gastrointestinal diseases [7]. In the last decade, several studies have shown a potential link between vitamin D deficiency and various diseases, especially systemic infections [8].…”

Section: Introductionmentioning

confidence: 99%

Prevalence and Factors Associated with Vitamin D Deficiency in Patients with COVID-19 in Parakou in 2021

Cissé,

Adaba,

Gounongbé

et al. 2023

OJEpi

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Introduction: Coronavirus 19 disease (COVID-19) often presents several serious complications in patients. 25-hydroxyvitamin D [25(OH)D] deficiency is considered a risk factor for severe forms of the disease. Objective: The objective of this work was to determine the prevalence and factors associated with vitamin D deficiency in patients with COVID-19 in Parakou in 2021. Methods: The method used was a descriptive and analytical cross-sectional study with prospective data collection that covered the period of August 1 , 2021, to December 30, 2021. It concerned patients with COVID-19, symptomatic or not, in the commune of Parakou, selected by non-probability sampling. The 25(OH)D assay was performed by an enzyme immunoassay using the heterogeneous phase competition technique. Logistic regression was used to determine the factors associated with 25(OH)D deficiency at the 5% threshold. Results: A total of 197 patients with COVID-19 were included in the study with a mean age of 35.4 ± 15.2 years; with a female predominance (52.3%). The overall prevalence of 25(OH)D deficiency was 31.5% (95% CI [25.1 -38.5]); it was 32.0% in females and 30.8% in males. 25(OH)D deficiency was more observed in patients ≥ 60 years than in patients < 60 years with no significant difference (p = 0.121), and in females (32.0%) than in males (30.8%) with no significant difference either (p = 0.857). Diabetes (p = 0.036), overweight or obesity (p = 0.032), severe disease forms (p = 0.003) and rhinitis (p = 0.009) were significantly associated with 25(OH)D deficiency. Conclusion: One-third of patients with COVID-19 in Parakou in 2021 were 25(OH)D deficient. 25(OH)D deficiency is associated with the severe form of How to cite this paper: Cissé, I.M., Adaba,

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La vitamine D chez l’adulte : recommandations du GRIO

Cited by 75 publications

References 66 publications

Sun Exposure Score and Vitamin D Levels in Moroccan Women of Childbearing Age

Sun Exposure Score and Vitamin D Levels in Moroccan Women of Childbearing Age

Vitamin D and COVID-19 Severity in Hospitalized Older Patients: Potential Benefit of Prehospital Vitamin D Supplementation

Prevalence and Factors Associated with Vitamin D Deficiency in Patients with COVID-19 in Parakou in 2021

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