Lab-on-a-chip sensing devices for biomedical applications

Sengupta, Pavel; Khanra, Kalap; Chowdhury, Amit Roy; Datta, Pallab

doi:10.1016/b978-0-08-102420-1.00004-2

Cited by 32 publications

(27 citation statements)

References 180 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…As a thermosetting material, resins are endowed with enhanced stability at high temperatures, chemical resistance, transparency, and very high resolution with small features. However, the most striking disadvantage of these materials is their high cost [ 13 , 36 ].…”

Section: Fabrication Of Microfluidic Devicesmentioning

confidence: 99%

“…Microfluidic devices can be used in a plethora of applications, seeking to overcome the difficulties or challenges in traditional assays. The evidence shows great potential in personalized medicine, disease diagnosis, chemical screening, cell culture, cell separation, cell treatment, drug screening, drug delivery, and DNA sequencing [ 13 , 34 , 78 , 79 ]. Moreover, the particles that can be obtained in microreactors can be further used in diverse areas, ranging from electronics, energy, and textiles to biotechnology, bioimaging, biosensing, and gene delivery [ 80 ].…”

Section: Applications Of Microfluidic Devicesmentioning

confidence: 99%

“…Such miniaturized microscale devices are useful instruments for carrying out operations like reactions, separations, or the detection of various compounds [ 4 , 10 ]. Depending on their application and functional particularities, microfluidic devices can also be found in the literature as microreactors [ 3 , 6 , 11 ], lab-on-a-chip [ 12 , 13 , 14 ], or organ-on-a-chip [ 4 , 15 , 16 ]. Providing their destination use, microfluidic chips can be manufactured from a broad range of materials, employing diverse fabrication methods [ 17 , 18 ].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Fabrication and Applications of Microfluidic Devices: A Review

Niculescu

Chircov

Bîrcă

et al. 2021

IJMS

386

208

View full text Add to dashboard Cite

Microfluidics is a relatively newly emerged field based on the combined principles of physics, chemistry, biology, fluid dynamics, microelectronics, and material science. Various materials can be processed into miniaturized chips containing channels and chambers in the microscale range. A diverse repertoire of methods can be chosen to manufacture such platforms of desired size, shape, and geometry. Whether they are used alone or in combination with other devices, microfluidic chips can be employed in nanoparticle preparation, drug encapsulation, delivery, and targeting, cell analysis, diagnosis, and cell culture. This paper presents microfluidic technology in terms of the available platform materials and fabrication techniques, also focusing on the biomedical applications of these remarkable devices.

show abstract

Section: Fabrication Of Microfluidic Devicesmentioning

confidence: 99%

Section: Applications Of Microfluidic Devicesmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Fabrication and Applications of Microfluidic Devices: A Review

Niculescu

Chircov

Bîrcă

et al. 2021

IJMS

386

208

View full text Add to dashboard Cite

show abstract

“…The most popular piezoelectric materials are piezoceramics (such as barium titanate (BaTiO 3 ) [ 64 ], lithium niobite (LiNbO 3 ) [ 65 , 66 ], lead zirconate titanate (PZT) [ 67 ], zinc oxide (ZnO) [ 68 ]), and polymers (such as polyvinylidene difluoride (PVDF) [ 69 ]). Piezoceramics consist of randomly oriented crystallites separated by grain boundaries.…”

Section: Physical Ultrasound Transducer Technologiesmentioning

confidence: 99%

Overview of Ultrasound Detection Technologies for Photoacoustic Imaging

2020

View full text Add to dashboard Cite

Ultrasound detection is one of the major components of photoacoustic imaging systems. Advancement in ultrasound transducer technology has a significant impact on the translation of photoacoustic imaging to the clinic. Here, we present an overview on various ultrasound transducer technologies including conventional piezoelectric and micromachined transducers, as well as optical ultrasound detection technology. We explain the core components of each technology, their working principle, and describe their manufacturing process. We then quantitatively compare their performance when they are used in the receive mode of a photoacoustic imaging system.

show abstract

“…The handling of small sample volumes, scalability, integration of multiple functions and fields, low operating costs, low energy consumption, and so forth are some of the already known advantages of systems miniaturization; however, an inherent problem in these small devices is in the manufacture of moving parts for the manipulation of fluids or samples. That is why techniques based on electrokinetic effects arise that do not need moving parts [ 2 ]. The microsystem known as a laboratory on a chip, with size from millimeters to centimeters, facilitates the implementation of many laboratory tasks, which include sample preparation, mixing, separation, manipulation, control, detection, and analysis [ 3 ].…”

Section: Introductionmentioning

confidence: 99%

Start-Up Electroosmotic Flow of Multi-Layer Immiscible Maxwell Fluids in a Slit Microchannel

et al. 2020

View full text Add to dashboard Cite

In this investigation, the transient electroosmotic flow of multi-layer immiscible viscoelastic fluids in a slit microchannel is studied. Through an appropriate combination of the momentum equation with the rheological model for Maxwell fluids, an hyperbolic partial differential equation is obtained and semi-analytically solved by using the Laplace transform method to describe the velocity field. In the solution process, different electrostatic conditions and electro-viscous stresses have to be considered in the liquid-liquid interfaces due to the transported fluids content buffer solutions based on symmetrical electrolytes. By adopting a dimensionless mathematical model for the governing and constitutive equations, certain dimensionless parameters that control the start-up of electroosmotic flow appear, as the viscosity ratios, dielectric permittivity ratios, the density ratios, the relaxation times, the electrokinetic parameters and the potential differences. In the results, it is shown that the velocity exhibits an oscillatory behavior in the transient regime as a consequence of the competition between the viscous and elastic forces; also, the flow field is affected by the electrostatic conditions at the liquid-liquid interfaces, producing steep velocity gradients, and finally, the time to reach the steady-state is strongly dependent on the relaxation times, viscosity ratios and the number of fluid layers.

show abstract

Lab-on-a-chip sensing devices for biomedical applications

Cited by 32 publications

References 180 publications

Fabrication and Applications of Microfluidic Devices: A Review

Fabrication and Applications of Microfluidic Devices: A Review

Overview of Ultrasound Detection Technologies for Photoacoustic Imaging

Start-Up Electroosmotic Flow of Multi-Layer Immiscible Maxwell Fluids in a Slit Microchannel

Contact Info

Product

Resources

About