Water scarcity is a global challenge that hinders human development. In recent years, electrostatic fog collection technology has emerged as a promising technology to alleviate this issue. Although electrostatic fog collectors based on a variety of electrode structures have been developed previously, there has been less research into other factors affecting the efficiency of electrostatic fog collection (e.g. electrical factors, environmental factors, etc), which has delayed the commercial application of the technology. In this paper, we experimentally investigate the effects of power supply polarity, voltage, airflow direction, airflow velocity, fog concentration and temperature on collection efficiency using a typical wire-mesh electrode fog collector as an example. The results show that both electrical and environmental factors influence the collection efficiency by changing the charge and the electric field force of the droplets. Negative polarity corona and high voltage are more favorable for fog collection. High velocity airflow and high fog concentration increase the amount of water collected due to the ability to bring more droplets into the electric field. However, the collection efficiency is reduced by the weakening of the corona discharge. High temperature accelerates the evaporation of fog droplets, which is not favorable for fog collection. In conclusion, this work will not only contribute to revealing the underlying mechanisms of the electrostatic fog collection but also will guide the development of highly efficient fog collectors.