Label-free detection of glypican-3 using reduced graphene oxide /polyetherimide/gold nanoparticles enhanced aptamer specific sensing interface on light-addressable potentiometric sensor

Field-Effect Sensors Combined with the Scanned Light Pulse Technique: From Artificial Olfactory Images to Chemical Imaging Technologies

“…As for the applications, many studies are directed to biosensing applications, including the detection of DNA hybridization [56,91], determination of glucose [92,93] and okadaic acid [94], as well as immunoassays of antigens [95]. Many studies are especially oriented to the detection of clinical biomarkers such as circulating tumor cells [96], alphafetoprotein [97], 1,5-anhydroglucitol [98], glypican-3 [99], and low-density lipoprotein [100]. The light-addressing technologies are also applied to cells, including the detection of extracellular acidification due to metabolism [67,101], light absorption of live cells [102], action potentials of cardiomyocytes [103], and apoptosis [104].…”

A simple and ultra‐sensitive electrochemical sensing approach for detection of arsenic (v) in drinking water

“…Critical parameters for any analytical method include the limit of detection (LOD) and the limit of quantification. LOD is the lowest template level that can tell a template from being empty, while LOQ is the smallest that can be determined with more certainty [39,40]. The calibration curve method was used to determine the limit of detection using Figure 5d.…”

Carbon-based photoelectrochemical sensors: recent developments and future prospects

“…Thus, to address this limitation, rGO has been studied as an excellent electron acceptor and transmitter with high electron mobility, which can promote the light absorption and charge transfer in PEC systems. Li et al 58 developed an unmarked detection biosensor for glypican-3 protein by immobilizing an aptamer on a silicon-based light-addressable potential sensor chip modified with the composite of rGO/PEI/AuNPs. The formation of a glypican-3-glypican-3 complex at the sensing interface induced a potential change on the sensitive film surface, resulting in a corresponding offset response in the photocurrent–voltage curve when a bias voltage was applied to the electrode system.…”