Label-free electrochemical detection of cancer biomarkers DNA and anti-p53 at tin oxide quantum dot-gold-DNA nanoparticle modified electrode

Richard, Yesurajan Allwin; Lincy, Sebastinbaskar Aniu; Piraman, Shakkthivel; Dharuman, Venkataraman

doi:10.1016/j.bioelechem.2023.108371

Cited by 11 publications

(1 citation statement)

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“…In another attempt, L-cysteine-functionalized ZnS QDs were developed for the fM detection of miR-200a, an ovarian cancer biomarker [ 117 ]. Richard and colleagues developed a label-free electrochemical DNA biosensor using a nanocomposite made of SnO 2 QDs and GNPs for the detection of lung cancer biomarkers [ 118 ]. A nanocomposite-based electrochemical biosensor was developed using MPA-capped CdTe/CeSe/ZnSe QDs covalently linked to poly(propylene imine) (PPI) via EDC/NHS coupling and utilized for the immobilization of ChOx and detection of cholesterol [ 119 ].…”

Section: Various Nanomaterial-modified Electrodesmentioning

confidence: 99%

Recent Developments in the Design and Fabrication of Electrochemical Biosensors Using Functional Materials and Molecules

Theyagarajan

Kim

2023

Biosensors

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Electrochemical biosensors are superior technologies that are used to detect or sense biologically and environmentally significant analytes in a laboratory environment, or even in the form of portable handheld or wearable electronics. Recently, imprinted and implantable biosensors are emerging as point-of-care devices, which monitor the target analytes in a continuous environment and alert the intended users to anomalies. The stability and performance of the developed biosensor depend on the nature and properties of the electrode material or the platform on which the biosensor is constructed. Therefore, the biosensor platform plays an integral role in the effectiveness of the developed biosensor. Enormous effort has been dedicated to the rational design of the electrode material and to fabrication strategies for improving the performance of developed biosensors. Every year, in the search for multifarious electrode materials, thousands of new biosensor platforms are reported. Moreover, in order to construct an effectual biosensor, the researcher should familiarize themself with the sensible strategies behind electrode fabrication. Thus, we intend to shed light on various strategies and methodologies utilized in the design and fabrication of electrochemical biosensors that facilitate sensitive and selective detection of significant analytes. Furthermore, this review highlights the advantages of various electrode materials and the correlation between immobilized biomolecules and modified surfaces.

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Section: Various Nanomaterial-modified Electrodesmentioning

confidence: 99%