Label-free electrochemiluminescent immunosensor for α-fetoprotein: performance of Nafion–carbon nanodots nanocomposite films as antibody carriers

Abstract

A simple and highly sensitive electrochemiluminescent immunosensor based on nanocomposite architecture of the one-pot synthesized carbon nanodots and Nafion composite film was proposed for the detection of α-fetoprotein.

Application of an Electrochemical Immunosensor with a MWCNT/PDAA Modified Electrode for Detection of Serum Trypsin

“…Some researchers have attempted to circumvent this issue by fixing the biomolecules using chemical bonding, which not only increases the stability of the fixation, but also reduces steric hindrance. However, this approach might lead to a molecular conformation change and reduced biological activity of the fixed biomolecules [16–19]. Based on the advantages and disadvantages of these two fixation methods, in this study, we used combined the biological analog interface and self-assembly technology to fix the biomolecules onto the sensor surface, which preserved the spatial conformation and the biological activity of the biomolecules.…”

Photoluminescent Detection of Nitrite with Carbon Nanodots Prepared by Microwave-assisted Synthesis

“…4 An increasing number of applications based on CNDs have been carried out, such as cell imaging, 5 dye degradation, 6 pH determination, 7 chemiluminescence, 8 and immunoassay. 9 These CND applications make the most of several favorable properties of CNDs such as size-and excitation wavelength-dependent luminescence emission, photostability, and biocompatibility. 10 Analytical applications of CNDs have been also reported for the detection of metal ions 11 and phosphate, 12 utilizing CND-metal ion affinity based on the carboxylic functionality of the CNDs surface.…”

The synthesis of Ag@CQDs composite and its electrochemiluminescence application for the highly selective and sensitive detection of chloride

“…The CQDs particles were synthesized according to the literature [35]. Briefly, D-Glucose (0.75 g) was dissolved in 40 ml ethylene glycol/H 2 O (1:1, V/V).…”

“…This could be achieved by CQDs doping with other elements, such as Si and N [32][33][34]. However, to the best of our knowledge only a handful of applications of fabricated CQDs-based ECL biosensors have been reported [18,35], especially for Cl − sensing. For example, Ding et al [36] synthesized an Ag@CQDs with relevant ECL intensity, which can be increased by mixing 100 μM S 2− with the Ag@CQDs.…”