2021
DOI: 10.21203/rs.3.rs-1055533/v1
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Label-Free LC-MS/MS Proteomics Analyses Reveal Proteomic Changes In Oxidative Stress And The SOD Antioxidant Strategy In TM Cells.

Abstract: Background: Treatment for glaucoma has traditionally been limited to reducing intraocular pressure (IOP). Inhibiting oxidative stress in the trabecular meshwork (TM) is regarded as a new treatment for glaucoma; however, the effects do not meet expectations. Exploring the mechanism by which oxidative stress and antioxidant stress occur in TM cells will offer clues to aid the development of new treatments.Methods and results: In our study, we cultured TM cells and used H2O2 and SOD to induce and inhibit oxidativ… Show more

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