Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2; COVID-19), is a novel virus that has swept the world causing illness and death. Youth are at a heightened risk of experiencing increased rates of abuse given necessary measures required to slow the spread of the virus (e.g., indefinite school closures). We analyzed data from New York City’s Administration for Children’s Services (ACS) to investigate the frequency of child maltreatment prevention service case openings during this time of unprecedented stress. Two descriptive investigations were conducted. An examination of trend lines demonstrated that for 2013-2019, New York City’s new prevention case openings have consistently peaked in the month of March, for all seven years. New prevention case service openings in March 2020 do not peak, as they do in the preceding seven years. An independent samples t-test indicated that the frequency of case openings of March 2020 is significantly different than the frequency of case openings in March 2013-2019. Further, a Poisson regression model estimated that the odds of opening a new child maltreatment prevention case post-COVID-19 are 179% lower than opening a new child maltreatment case pre-COVID-19 (OR = -0.79, p < .001). These findings highlight the necessity of future research and innovation regarding child maltreatment prevention and intervention services during a global pandemic. This study has important implications for identification, prevention, and documentation for current support, and recommendations for local governments, community members, and practitioners are provided.