Laboratory Assessment of the Molluscicidal Activity of B-2, a New Chemical Against Oncomelania Nosophora

Kajihara, Noriaki; Horimi, Toshimasa; Minai, Masaru; Hosaka, Yukio

doi:10.7883/yoken1952.32.185

JJMSB

1979

DOI: 10.7883/yoken1952.32.185

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Laboratory Assessment of the Molluscicidal Activity of B-2, a New Chemical Against Oncomelania Nosophora

Noriaki Kajihara¹,

Toshimasa Horimi²,

Masaru Minai³

et al.

Abstract: SUMMARY: Laboratory trials of sodium 2 ,5 dichloro-4-bromophenol named B-2 f or the molluscicidal effect against Oncomelania nasophora were carried out by Komiya's immersion technique. The values of LC50 of B-2 varied from 0 .38 ppm to 0 .54 ppm depending on the collection time of the snail . They were almost equal to those of NaPCP, but lower than those of Niclosamide . In the tests of toxicity to carp, rainbow trout and killifish , B-2 showed lower toxicity than NaPCP. Some aspects of mollusciciding applicat… Show more

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Cited by 11 publications

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“…Laboratory experiments of the molluscicidal activity of 2,5-dichloro-4-bromophenol named B-2 have previously been reported by the present authors (Kajihara et al, 1979). The results indicated its promising cidal effect against Oncomelania nosophora as well as its rather low toxicity to fish and mammals.…”

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confidence: 62%

Field Assessment of B-2 as a New Molluscicide for the Control of Oncomelania Nosophora

Kajihara¹,

Horimi²,

Minai³

et al. 1979

JJMSB

Self Cite

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SUMMARY: Sodium 2,5-dichloro-4-bromophenol named B-2 was evaluated for application in the field as a molluscicide against Oncomelania nosophora. A dosage of 10 g/m2 as 25% liquid form or 25 g/m2 as 10% granular form of B-2 was suggested as a standard dose for the control of O. nosophora. The residual concentration of B-2 in the soil after application was observed to decrease more rapidly than did that of NaPCP. The residual level of B-2 in the rice grains harvested from the paddy field in which the chemical was applied at most 4 times during the planting season did not exceed 0.03 ppm.

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supporting

confidence: 62%

Field Assessment of B-2 as a New Molluscicide for the Control of Oncomelania Nosophora

Kajihara¹,

Horimi²,

Minai³

et al. 1979

JJMSB

Self Cite

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The effects of bayluscide and malathion on the mortality and infectivity of Schistosoma mansoni cercariae

Tchounwou

Englande

Malek

et al. 1992

Environ. Toxicol. Water Qual.

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Laboratory experiments were conducted to assess the effects of bayluscide and malathion on the mortality and infectivity of Schistosoma mansoni cercariae. Mortality of cercariae varied with time of exposure and concentration of tested chemicals. The LC5, LC50, and LC95 for bayluscide were 0.04, 0.07, and 0.10 ppm after 2 h of exposure; 0.03, 0.04, and 0.06 ppm after 4 h of exposure; and 0.02, 0.03, and 0.05 ppm after 6 h of exposure, respectively. Malathion gave LC5, LC50, and LC95 values of 59.16, 107.07, and 193.78 ppm after 2 h of exposure; and 39.79, 69.36, and 120.89 ppm after 4 h of exposure, respectively. Sublethal concentrations of bayluscide and malathion significantly reduced the rate of infection of laboratory mice by S. mansoni cercariae (p < 0.01). Approximately 1.50 and 0.00% of adult worms were recovered by autopsy of mice whose cercariae were preexposed for only 1 h to 0.04 ppm of bayluscide and 50.00 ppm of malathion, respectively. These results clearly show that bayluscide is much more toxic to cercariae than to snail intermediate hosts cited in the literature, and that malathion possesses some cercaricidal properties at concentrations expected to be achieved in the field.

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Molluscicides against the snail-intermediate host of Schistosoma: a review

et al. 2021

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Schistosomiasis, a neglected tropical disease (NTD), is one of the most prevalent parasitoses in the World. Certain freshwater snail species are the intermediate host in the life cycle of schistosome species. Controlling snails employing molluscicides is an effective, quick, and convenient intervention strategy to prevent the spread of Schistosoma species in endemic regions. Advances have been made in developing both synthetic molluscicides and molluscicides derived from plants. However, at present, the development of molluscicides is not adapted to the actual demand for snails and schistosoma controlling. We undertake a systematic review of exploitation and application of synthetic molluscicides and molluscicides derived from plants to combat intermediate host snails. The detailed molluscicidal activity, structure–activity relationship, structural feature, and possible mechanism of some molluscicides are also highlighted, which may afford an important reference for the design of new, more effective molluscicides with low environmental impact and realize the aim of controlling schistosome at transmission stages. Supplementary Information The online version contains supplementary material available at 10.1007/s00436-021-07288-4.

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Laboratory Assessment of the Molluscicidal Activity of B-2, a New Chemical Against Oncomelania Nosophora

Cited by 11 publications

References 2 publications

Field Assessment of B-2 as a New Molluscicide for the Control of Oncomelania Nosophora

Field Assessment of B-2 as a New Molluscicide for the Control of Oncomelania Nosophora

The effects of bayluscide and malathion on the mortality and infectivity of Schistosoma mansoni cercariae

Molluscicides against the snail-intermediate host of Schistosoma: a review

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