Laboratory evaluation of endocrine hypertension

Winter, William E.; Harris, Neil

doi:10.1016/b978-0-12-818277-2.00011-x

Handbook of Diagnostic Endocrinology 2021

DOI: 10.1016/b978-0-12-818277-2.00011-x

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Laboratory evaluation of endocrine hypertension

William E. Winter

Neil Harris

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2023

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Exploring the potential of intranasal drug delivery systems in the management of hypertension

Hassan

Gad

Shaker

et al. 2023

RPS Pharmacy and Pharmacology Reports

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Objective The current review gives an overview on the anatomical and cellular structure of the nasal cavity. It presents some possibilities and different techniques to enhance the drug penetration through the nasal barrier. It comprehensively details the intranasal drug delivery system and the treatment modalities of hypertension, with emphasis on nanotechnology-based products. Methods Gather published works about the research progression in the systemic delivery of antihypertensive drugs through the nasal epithelium, the formulation tactics and their related in vitro, ex vivo and in vivo assessment technologies in this field. Key findings Intranasal drug delivery is one of the potential routes for avoiding the first pass effect, lowering drug doses, reducing systemic side effects of most antihypertensive drugs and enhancing drug bioavailability. Conclusions Compared to oral medications, nasal medications often have better bioavailability and fewer adverse effects at the same dosage, which encourages pharmaceutical companies to manufacture additional medications in the form of nasal formulations intended for systemic treatment.

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Exploring the potential of intranasal drug delivery systems in the management of hypertension

Hassan

Gad

Shaker

et al. 2023

RPS Pharmacy and Pharmacology Reports

View full text Add to dashboard Cite

show abstract

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Laboratory evaluation of endocrine hypertension

Cited by 1 publication

References 153 publications

Exploring the potential of intranasal drug delivery systems in the management of hypertension

Exploring the potential of intranasal drug delivery systems in the management of hypertension

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