Laboratory Evaluation of Vocal Fold Paralysis and Paresis

White, Michelle; Meenan, Kirsten; Patel, Tirth V.; Jaworek, Aaron; Sataloff, Robert T.

doi:10.1016/j.jvoice.2016.07.022

Cited by 14 publications

(1 citation statement)

References 23 publications

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“…However, the parameters gradually improved until 3 months after IL but slightly worsened by 6 months after IL. Acoustic parameters can be judged to represent the objective voice quality of patients with UVCP [17][18][19]. Among the acoustic parameters, CPP was the only statistically significant parameter.…”

Section: Discussionmentioning

confidence: 99%

The Investigation of Hyaluronic Acid (The Chaeum Premium No.2®) to Evaluate the Efficacy and Safety for Injection Laryngoplasty in Unilateral Vocal Cord Paralysis: A Single Center, Phase II Trial

Park,

Kim

2024

J Korean Soc Laryngol Phoniatr Logop

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Background and Objectives This study aimed to evaluate the clinical efficacy and safety of hyaluronic acid (HA) (The Chaeum Premium No.2®) for injection laryngoplasty (IL) in unilateral vocal cord paralysis (UVCP) patients.Materials and Method This clinical trial has been registered with the clinical research information service of the Republic of Korea (No. KCT0007597). Ten patients with UVCP were enrolled. Auditory-perceptual evaluation, acoustic analysis, aerodynamic analysis, electroglottography, laryngoscopy, and voice handicap index (VHI)-30 were assessed before injection, at 1, 3, and 6 months after injection.Results All auditory-perceptual parameters gradually showed statistically significant improvements at 1, 3, and 6 months after injection. Acoustic, aerodynamic parameters, electroglottography, and VHI-30 showed gradual improvements at 1 and 3 months after injection. Then, they showed slight deterioration 6 months after injection. There were no adverse effects in all patients.Conclusion IL using HA is an effective and safe treatment for UVCP patients.

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Section: Discussionmentioning

confidence: 99%