Laboratory experience with a magnetically guided intravascular catheter system

Cares, Herbert L.; Hale, J.R.; Montgomery, D.B.; Richter, Howard A.; Sweet, William H.

doi:10.3171/jns.1973.38.2.0145

Cited by 27 publications

(8 citation statements)

References 11 publications

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“…The concept of magnetically guided intravascular devices has existed for decades (41)(42)(43)(44)(45)(46). Despite the long and checkered history of using magnetism to direct intravascular devices (5), there are currently no viable magnetic guidewire/catheter products or commercially available robotic systems to magnetically manipulate such devices for neurovascular applications, where the active steering capability is most needed.…”

Section: Discussionmentioning

confidence: 99%

Telerobotic neurovascular interventions with magnetic manipulation

et al. 2022

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Advances in robotic technology have been adopted in various subspecialties of both open and minimally invasive surgery, offering benefits such as enhanced surgical precision and accuracy with reduced fatigue of the surgeon. Despite the advantages, robotic applications to endovascular neurosurgery have remained largely unexplored because of technical challenges such as the miniaturization of robotic devices that can reach the complex and tortuous vasculature of the brain. Although some commercial systems enable robotic manipulation of conventional guidewires for coronary and peripheral vascular interventions, they remain unsuited for neurovascular applications because of the considerably smaller and more tortuous anatomy of cerebral arteries. Here, we present a teleoperated robotic neurointerventional platform based on magnetic manipulation. Our system consists of a magnetically controlled guidewire, a robot arm with an actuating magnet to steer the guidewire, a set of motorized linear drives to advance or retract the guidewire and a microcatheter, and a remote-control console to operate the system under real-time fluoroscopy. We demonstrate our system’s capability to navigate narrow and winding pathways both in vitro with realistic neurovascular phantoms representing the human anatomy and in vivo in the porcine brachial artery with accentuated tortuosity for preclinical evaluation. We further demonstrate telerobotically assisted therapeutic procedures including coil embolization and clot retrieval thrombectomy for treating cerebral aneurysms and ischemic stroke, respectively. Our system could enable safer and quicker access to hard-to-reach lesions while minimizing the radiation exposure to physicians and open the possibility of remote procedural services to address challenges in current stroke systems of care.

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Section: Discussionmentioning

confidence: 99%

Telerobotic neurovascular interventions with magnetic manipulation

et al. 2022

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“…2 3 4 5 6 7 The proximal portion was made of polyethylene and the distal portion of soft silicone rubber. The distal section measured only 1.3 mm in outer diameter and was 7 cm in length.…”

Section: The Pre-balloons Eramentioning

confidence: 99%

The beginning and the evolution of the endovascular treatment of intracranial aneurysms: from the first catheterization of brain arteries to the new stents

Guglielmi

2009

J NeuroIntervent Surg

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“…Cares et al [50] described a number of therapeutic applications in the cerebrovasculature using magnetically guided catheters. These included injection of iron particles (0.4 to 4.0 micron diameter suspended in human albumin) into experimental saccular aneurysms, selective angiography and obliteration of an experimental aneurysm by introduction of a balloon detachable from the catheter tip.…”

Section: Cerebrocajrular Applicationsmentioning

confidence: 99%

A Review of Medical Applications of Magnet Attraction and Detection

Driller

Frei

1987

Journal of Medical Engineering & Technology

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IntroductionA magnetic field will develop forces on magnetic objects which lie within the field, as shown in figure 1. These forces will tend to align the magnetic axis of the object with the field axis as this is the position of stable equilibrium. In addition, in the presence of a field gradient, there will be a net translational force on the object. The magnetic object will also perturb the field, which effect can be used for detection of the object. These effects have been used to good advantage in the solution of many dissimilar medical problems. In some cases, this design information did not remain readily accessible after other techniques superseded the magnetic designs. The purpose of this review is to gather design information of selected applications and so facilitate its availability for other uses. Diagnostic applications Detection of trace quantities of magnetic materialsFerromagnetic materials can be detected in the body using magnetic measurement techniques. Iron oxides are widely distributed and trace quantities can be incorporated into the body through a variety of channels. One such channel is respiration. A method developed to measure trace quantities of iron in the lung involves magnetizing the particles, either both lungs at one time or local areas sequentially. The remanent magnetization is then measured with a gradiometer which employs a superconducting quantum interference device (SQUID).Cohen and Nemoto [ 11 described the magnetization and relaxation events which occur. An understanding of these processes is important for proper evaluation since tht data are very dependent upon elapsed time. Freedman et al. [ 2 ] used this technique and observed significant differences in trace quantities of ferro-magnetic materials within the lungs of controls, welders, machinists and other occupations.The hepatic store of iron is an important component in metabolism and an important piece of diagnostic data. This data can be measured from liver tissue obtained via needle biopsy. A non-invasive method involves measurement of magnetic susceptibility of the liver. Bauman and Hoffman [3] described a susceptometer utilizing a large toroidal transformer with small air gap. It measured the magnetic susceptibility of materials within the gap and was used to detect differences of iron concentration in the in situ livers of control and iron-loaded rats. Significant differences were seen in the live rat between livers containing 0.36 mg Fe/gm liver (non-loaded controls), 6.5 mg Fe/gm liver (Fe introduced parenterally) and 11.5 mg Fe/gm liver (Fe introduced intravenously). A larger unit for hepatic iron measurements in humans was discussed. Detection of radio-opaque contrast materialsRadio-opaque contrast material, utilizing slurries of inert barium, are used for gastro-intestinal (GI) radiography. There is little control of this material after it is ingested. This results, occasionally, in inadequate coating of the GI tract or too rapid movement of the material through the tract. Frei et al. 14-1 developed a ferro...

show abstract

Laboratory experience with a magnetically guided intravascular catheter system

Cited by 27 publications

References 11 publications

Telerobotic neurovascular interventions with magnetic manipulation

Telerobotic neurovascular interventions with magnetic manipulation

The beginning and the evolution of the endovascular treatment of intracranial aneurysms: from the first catheterization of brain arteries to the new stents

A Review of Medical Applications of Magnet Attraction and Detection

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