Laboratory markers has many Valuable Parameters in the discrimination between acute appendicitis and renal colic

Acar, Ethem; Özcan, Önder; Deliktaş, Hasan; Beydilli, Halil; Kırlı, İsmail; Alataş, Ömer Doğan; Şahin, Cem; Yıldırım, Birdal; Belli, Aslı Akın

doi:10.5505/tjtes.2015.69488

Cited by 14 publications

(23 citation statements)

References 11 publications

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“…However, (although diagnostic value of RDW in complicated AA has been studied (17,18), Our results did not reveal any difference in RBC between the groups. Consistent with a previous study that included 215 patients and showed that the level of RDW was statistically significantly higher in AA (25), in this study, RDW was found to be an independent diagnostic factor for complicated AA.…”

Section: Discussionsupporting

confidence: 92%

Investigation of Predictive Value of Complete Blood Count in the Diagnosis of Acute Complicated Appendicitis

Günay¹,

Tasdoven²,

Kozan³

et al. 2019

Haseki

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Amaç: Komplike akut apandisitin (AA) ayırıcı tanısında tam kan sayımının kullanılabileceği konusunda tartışmalar devam etmektedir. Bu çalışmada tam kan sayımının komplike AA ayırıcı tanısındaki kestirim değeri araştırıldı. Yöntemler: Ocak 2015 ile Ocak 2018 tarihleri arasında apendektomi ameliyatı olan hastaların dosyaları geriye dönük incelendi. Demografik verilerle tam kan sayımının sonuçları toplandı. Bulgular: İki yüz otuz beş hasta AA nedeni ile apendektomi ameliyatı oldu. Bu 235 hastadan, 164'ünde (%69,8) non-komplike AA tespit edilirken 71'inde (%30,2) komplike AA bulundu. Ortalama beyaz küre sayısı (WBC), kırmızı küre dağılım genişliği (RDW), trombositlerin sayımı ve plateletcrit serum düzeyleri komplike AA olan hastalarda anlamlı derecede yüksek (sırasıyla, p=0,001; p<0,001; p=0,049; p=0,006). Hem nötrofil sayısı hemde nötrofilin yüzdelik oranı komplike AA olan hastalarda anlamlı derecede yüksek bulundu (sırasıyla, p=0,001; p<0,01). Komplike olmayan AA'larla karşılaştırıldığında komplike AA olan hastalarda hem basofil-lenfosit oranı (BLR) hem de nötrofil-lenfosit oranı (NLR) anlamlı derecede yüksek bulundu (sırasıyla, p=0,001; p<0,01). Multivariant analiz ile yapılan incelemede WBC ve RDW'nin komplike AA'da bağımsız tanısal değeri olduğu tespit edildi [tahmini rölatif risk 5,079 %95 güven aralığı (GA): 2,29-11,24; p<0,001]; RDW için tahmini rölatif risk 1,412 (%95 GA:1,01-1,98; p=0,046). Komplike AA'da BLR için duyarlılık %67,35; özgüllük %64,04; pozitif kestirim değeri %44,6 ve negatif kestirim değeri %82 bulunurken NLR için duyarlılık %73,47; özgüllük %66,67; pozitif kestirim değeri %48,6 ve negatif kestirim değeri %85,4 olarak tespit edildi. Sonuç: Yüksek NLR BLR ve RDW değerleri ile birlikte artmış WBC ve nötrofil sayımı komplike AA'nın ayırıcı tanısında kullanılabilir. Anahtar Sözcükler: Akut apandisit, tam kan sayımı, komplike apandisit Aim: Whether it is possible to differentiate complicated from uncomplicated acute appendicitis (AA) by using complete blood count (CBC) is controversial. In this study, we analysed the predictive value of CBC in differentiating complicated from uncomplicated AA. Methods: In this retrospective study, we analyzed records of patients who underwent appendectomy in our clinic between January 1, 2015 and January 1, 2018. The demographic data and CBC reports were collected. Results: Two hundred thirty-five patients underwent appendectomy due to AA. Of the 235 patients, 164 (69.8%) had non-complicated and 71 (30.2%) had complicated AA. The mean white blood count (WBC), red cell distribution width (RDW), platelet and plateletcrit count were significantly higher in patients with complicated AA than in those with uncomplicated AA (p=0.001; p<0.01, p=0.049, and p=0.006, respectively). Both the mean neutrophil count and percentage were statistically higher in complicated AA patients (p=0.001 and p<0.01, respectively). The basophil-to-lymphocyte ratio (BLR) and neutrophilto-lymphocyte ratio (NLR) were significantly higher in patients with complicated AA (p=0.001 and p<0.01, respe...

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Section: Discussionsupporting

confidence: 92%

Investigation of Predictive Value of Complete Blood Count in the Diagnosis of Acute Complicated Appendicitis

Günay¹,

Tasdoven²,

Kozan³

et al. 2019

Haseki

View full text Add to dashboard Cite

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“…In parallel to these data, NLR value in our study was lower in flank pain due to urinary stone disease compared to no stone group (2.68 ± 1.86) which was statistically significant. However, our cut-off value was 2.16 and lower than those of Acer et al [6] and Uyeturk et al [27]. Additionally, WBC and PLT results were not statistically significant in the present study.…”

contrasting

confidence: 86%

The utility of the neutrophil-to-lymphocyte ratio in predicting urolithiasis in acute abdominal pain accompanied by flank pain

Akgün

Sinanoğlu

2019

The European Research Journal

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Objectives: To evaluate whether the neutrophil-to-lymphocyte ratio (NLR), can differentiate between urinary stone disease and inflammatory conditions in patients admitted to emergency department having acute abdominal pain accompanied by flank pain. Methods: Data of 191 patients with acute abdominal pain accompanied by flank pain admitted to emergency department in a single institution during 1 year period was retrospectively reviewed. Complete blood count and urine analysis were evaluated, the definitive diagnosis was established radiologically. The NLR was calculated as the absolute neutrophil count divided by the absolute lymphocyte count. The cut off value for the NLR in relation to stone status was calculated. Results: Of the 191 patients 51.3% (n = 98) were males, 48.7% (n = 93) were females (p > 0.05). White blood counts of the patients according to the presence of stone does not show a statistically significant difference (p > 0.05). NLR measurement of patients according to the presence of stone shows a statistically significant difference (p = 0.009). NLR of patients with urinary stones were significantly lower than patients without urinary stones. NLR measurements did not differ significantly according to stone location. A cutoff point of ≤ 2.16 for the NLR was determined according to the stone status of the patients. NLR values were higher in patients with acute abdominal pain/flank pain due to inflammatory pathologies. Conclusion: As the diagnosis and treatment of urolithiasis take long time and require elaborate methods, NLR may be used as a simple method in the differential diagnosis of pain due to urinary stone disease or inflammatory condition.

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“…Occlusion of capillaries and venules and finally venous ischemia develop following increased intraluminal pressure with obstruction of the lumen and associated lumen secretions developing in AA. Arterial ischemia finally occurs, and necrosis and perforation result [23,24]. IMA levels rise as a result of this ischemia.…”

Section: Discussionmentioning

confidence: 99%

The Diagnostic Values of Ischemia-Modified Albumin in Patients with Acute Abdominal Pain and Its Role in Differentiating Acute Abdomen

Yeniocak

Saraç

Yazıcıoğlu

et al. 2020

Emergency Medicine International

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Aim. The aim of this study was to evaluate the diagnostic value of serum ischemia-modified albumin (IMA) levels in patients presenting to the emergency department with acute abdominal pain and its use in differentiating acute surgical abdomen. Methods. This single-center prospective cross-sectional study included 334 adult patients who presented to the emergency department. These consisted of 194 patients (Group 1) with nontraumatic abdominal pain commencing in the preceding week, who were definitely diagnosed and either hospitalized in a specific department or planned for discharge, and a control group of 140 patients (Group 2). Results. The mean IMA value of the patients diagnosed with acute appendicitis was statistically significantly higher than that of the control group. The mean IMA value of the patients diagnosed with acute appendicitis, ovarian pathologies, and gastritis-peptic ulcer was statistically significantly higher than that of the nonspecific abdominal pain group. Conclusion. Serum IMA levels can be used as a diagnostic marker in patients with acute appendicitis. Furthermore, serum IMA levels in patients presenting to the emergency department with abdominal pain may be indicative of patients requiring surgery or of complicated cases, particularly in terms of acute appendicitis and ovarian pathologies.

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Laboratory markers has many Valuable Parameters in the discrimination between acute appendicitis and renal colic

Cited by 14 publications

References 11 publications

Investigation of Predictive Value of Complete Blood Count in the Diagnosis of Acute Complicated Appendicitis

Investigation of Predictive Value of Complete Blood Count in the Diagnosis of Acute Complicated Appendicitis

The utility of the neutrophil-to-lymphocyte ratio in predicting urolithiasis in acute abdominal pain accompanied by flank pain

The Diagnostic Values of Ischemia-Modified Albumin in Patients with Acute Abdominal Pain and Its Role in Differentiating Acute Abdomen

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