Laboratory methods for detecting the toxins of Clostridium difficile

Barbut, Frédéric; Petit, Jean‐Claude

doi:10.1007/978-2-8178-0903-8_10

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Evaluation and Management Of C Difficile Infection1

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2007

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“…The diagnosis of C difficile infection was confirmed when both stool culture and the detection of toxins A and B by rapid immunoassays were positive (18). The severity of the acute illness was evaluated using both medical records and a questionnaire assessing the presence and duration of digestive symptoms, including diarrhea, abdominal pain, fever, bleeding, passed mucous, amount of weight loss and vomiting.…”

Section: Evaluation and Management Of C Difficile Infectionmentioning

confidence: 99%

Low Risk of Irritable Bowel Syndrome afterClostridium difficileInfection

Piche

Vanbiervliet

Pipau

et al. 2007

Canadian Journal of Gastroenterology

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We have shown that while transient functional bowel disorder occurred in 34.7% of patients (eight of 23 patients) recently infected with C difficile, only 4.3% of patients (one of 23 patients) had symptoms indicative of IBS after three months (ie, postinfectious IBS). Because an age-related reduction in immune responsiveness has been documented, it can be speculated that the low incidence of postinfectious IBS may be explained by the older age of the study population. Therefore, it cannot be excluded that the findings may be different in younger patients.

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Section: Evaluation and Management Of C Difficile Infectionmentioning

confidence: 99%