Laboratory Tests of Uniform Fabric Impregnated with Mite Repellents

Bertram, D. S.; Page, Rob; Moss-Blundell, A. J.

doi:10.1136/jramc-113-03-02

Cited by 2 publications

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“…A number of different methods have been used to assess repellent efÞcacy against chiggers (Madden et al 1944, Snyder and Morton 1946, Bertram et al 1967, Kulkarni 1977, Breeden et al 1982, Buescher et al 1984, Clopton and Gold 1992, Ho and Fauziah 1993, Frances 1994, Frances and Khlaimanee 1996, Tilak et al 2001. The most widely used method for the in vitro evaluation of repellents against chiggers is a modiÞcation of the median effective dose (ED 50 ) doseÐresponse system Þrst reported by Bertram et al (1967) and Kulkarni (1977). Limitations of this method are the large number of chiggers required and the amount of time (30 min) for each test.…”

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Development of an In Vitro Method for the Evaluation of Candidate Repellents AgainstLeptotrombidium(Acari: Trombiculidae) Chiggers

et al. 2003

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We developed a rapid and economical in vitro procedure with which to evaluate the efficacy of candidate repellents against chiggers. The procedure requires only 5 min and a small number of chiggers to obtain a valid estimate of the median effective dose. We used this procedure to evaluate the repellent activity of 11 compounds against the chigger, Leptotrombidium imphalum Vercammen-Grandjean and Langston. Median effective doses were determined for 10 of the 11 compounds. DM-165-2 (N,N-diethyl-3-flurobenzamide) was the only compound that was significantly more effective than deet.

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