Driven by strong winds, huge ocean waves can cause devastating destruction to coastal regions during harsh weather events. There is growing evidence showing that extreme waves can occur in both shallow and deep waters. To protect the coast against the destructive power of huge waves, coastal protection facilities, such as seawalls, are often built along the coast. The integrity and stability of these coastal protection facilities are essential to the safety of coastal regions. Since huge waves are often accompanied by strong winds in real ocean environments, to fill the knowledge gap left by previous relevant studies, this study numerically investigates the hydrodynamic loads and overtopping of a coastal seawall model on a sloped beach under the coupled impact of an extreme wave group and wind. The influences of several main factors are considered, such as water depth, wind speed, and significant wave height. The research results reveal that strong wind can greatly increase the average overtopping rate and enhance the hydrodynamic loads exerted by the extreme wave group on the seawall.