Labyrinthine involvement in Behçet's syndrome

Abstract

We report the neuro-otological ndings in 26 consecutive patients with de nite and probable Behçet's syndrome unselected for audiovestibular complaints. Auditory and/or vestibular abnormalities were found in 19 (73 per cent) patients, with auditory involvement in 14 (54 per cent) and vestibular in 10 (38.5 per cent) of patients. Peripheral involvement was more common than central involvement for both auditory and vestibular lesions. Bilateral cochlear hearing impairment was the most common audiological nding, whereas unilateral peripheral dysfunction was the prevailing vestibular abnormality. No correlation has been found between audiovestibular lesions and other organ lesions, disease duration or age or sex of the patients. Moreover, there was a lack of interdependence between cochlear and vestibular labyrinthine lesions. We conclude that a full neuro-otological assessment in patients under investigation for Behçet's syndrome may reveal labyrinth involvement in a substantial proportion of patients. In view of the absence of a speci c diagnostic test for Behçet's syndrome, audiovestibular lesions may provide further diagnostic support for this disorder.

Cochleovestibular Dysfunction in Ankylosing Spondylitis

“…On the other hand, the involvement of the cochlea was more frequent than the involvement of the vestibular system. The lack of correlation between the dysfunction of the cochlea and the vestibular system can be explained by their different vascular supply [Pollack et al, 2001].…”

“…The rates of SNHL reported in the literature are 29.5-55% in rheumatoid arthritis [Kastanioudakis et al, 1995;Salvinelli et al, 2004], 24-55% in Behçet's disease [Ak et al, 2004;Evereklioğlu et al, 2001;Pollack et al, 2001], 46% in the Sjögren syndrome [Tumiati et al, 1997] and 58% in systemic lupus erythematosus [Andonopoulos et al, 1995]. SNHL in rheumatic diseases is bilateral, especially at high frequencies.…”

“…Kakani et al [1990] and King et al [2002] suggested that vestibular system dysfunction in rheumatoid arthritis is rare. Pollack et al [2001] reported that the peripheral and central parts of the vestibular system are affected by Behçet's disease. Evereklioğlu et al [2001] suggested that vestibular dysfunction was the fifth most frequent finding in Behçet's disease.…”

Audiological Findings in Autoimmune Hepatitis: Hearing Loss at High Frequencies

“…It may be due to vasculitis, ossicular involvement, neuritis or ototoxicity of the drugs used for the treatment of rheumatologic diseases (18). Thus, hearing loss may be seen in conductive, sensorineural or in mixed pattern in secondary AIED (5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(19)(20). Özcan et al suggested middle ear involvement for the reason of hearing loss in RA (18).…”

“…Bununla birlikte, otoakustik emisyon (OAE) gibi diğer testleri de içeren ve daha büyük örneklem büyüklüğüne sahip başka çalışmalara da ihtiyaç vardır. (5)(6)(7)(8)(9)(10)(11)(12)(13)(14). The inner ear pathologies caused by these disorders are commonly mild and slowly progressive whereas primary AIED is characterized by sudden onset, commonly bilateral, fluctuant and progressive sensorineural hearing loss (SNHL) with accompanying vertigo in some occasions.…”