“…Approximately half of the published genetic studies found the C allele associated with asthma, asthma severity or aspirin intolerance (105,(115)(116)(117)(118). The other studies, including two also investigating another promoter polymorphism ()1072 G>A) did not detect an association with those same phenotypes (109,(119)(120)(121)(122)(123)(124)(125)) (see Table 3). Interest- (113) 3¢UTR, 3¢ untranslated region; 5¢UTR, 5¢ untranslated region; A, asthma; AD, atopic dermatitis; AIA, aspirin intolerant asthma; AICU, aspirin intolerant chronic urticaria; AL, allergic; ALOX5, 5-lipoxygenase; ALOX5AP, 5-lipoxygenase activating protein; AR, allergic rhinitis; ATA, aspirin tolerant asthma; C, controls (population); C, coding region (location); I, intronic; LTA4H, leukotriene A4 hydrolase; LTC4S, leukotriene C4 synthase; NAL, nonallergic; P, promoter; SA, severe asthma; SNP, single nucleotide polymorphism.…”