Lack of clinicopathologic correlation in the diagnosis of oral lichen planus based on the presently available diagnostic criteria and suggestions for modifications

Meij, E.H. van der; Waal, I. van der

doi:10.1034/j.1600-0714.2003.00125.x

Cited by 678 publications

(596 citation statements)

References 18 publications

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“…Therefore, oral lichenoid lesions (OLLs) were excluded. The diagnosis of the lesions in this patient was made based on the modified criteria of van der Meij et al 16 Moreover, the lesions in this case showed no signs of oral candidiasis and there was no presence of any contributing factors causing Candida infection in this patient. Finally, the definite diagnosis of her oral lesions from 2 biopsies together with the oral manifestations confirmed OLP.…”

Section: Discussionmentioning

confidence: 99%

Squamous cell carcinoma arising in plaque-like oral lichen planus: A case report

Prapinjumrune¹,

Chaisuparat²,

Kobkan³

2017

Dent. Med. Probl.

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Section: Discussionmentioning

confidence: 99%

Squamous cell carcinoma arising in plaque-like oral lichen planus: A case report

Prapinjumrune¹,

Chaisuparat²,

Kobkan³

2017

Dent. Med. Probl.

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“…To the best of our knowledge, no one reported so far the association between OLP and HT. most recent diagnostic criteria [3]. All patients were screened for the presence of IgG anti-HCV antibodies by third-generation ELISA, and positive results were confirmed by means of second-generation RIBA.…”

Section: Introductionmentioning

confidence: 99%

Possible link between Hashimoto's thyroiditis and oral lichen planus: a novel association found

et al. 2012

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Objectives Hashimoto's thyroiditis as well as lichen planus has been associated to a number of disorders, generally of auto-immune origin. A novel possible association between oral lichen planus (OLP) and Hashimoto's thyroiditis (HT) is here proposed on the basis of a cross-sectional survey. Materials and methods One hundred and five unrelated OLP patients were considered. Diagnosis of HT was based on positive serum anti-TPO, anti-Tg, TSH levels and the typical ultrasound pattern of the thyroid gland. Results In the present survey, the prevalence of HT in the OLP group was 14.3 % whereas the prevalence of HTrelated hypothyroidism in the general population was reported to be equal to 1 %. By Fisher's exact test, it was revealed that the difference between our data and historical prevalence of HT was found statistically significant. Conclusion Actually, there is no definitive hypothesis that could explain the coexistence of OLP and HT. However, considering the onset timing of HT followed by OLP in 93.3 % of our series, we suspected a causal or predisposing role for HT. Specifically, we believe that in HT patients, circulating thyroid antibodies could contribute to trigger an organ-specific auto-immune response also in the oral mucosa or skin, leading to the development of LP lesions. Clinical relevance Because of the large number of cases of asymptomatic chronic auto-immune thyroiditis, it would be useful that women over 40 years of age affected by OLP were screened for thyroid dysfunction, particularly HT.

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“…Therefore, a higher rate of disagreement observed for cases of lichen planus could be an expected finding, mainly in relation to oral leukoplakia 21 . The differential diagnosis between these pathologic entities may be difficult, particularly when clinical and histopathologic findings are not compatible 20,22 . However, the high performance for the oral immunologically mediated lesions group in the diagnostic tests indicates that dentists had reasonable skills to diagnose this group of lesions.…”

Section: Discussionmentioning

confidence: 99%

Agreement between clinical and histopathologic diagnoses and completeness of oral biopsy forms

et al. 2016

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The present study aimed to assess the rate of agreement between clinical and histopathological diagnoses and to report the frequency of completed forms for specimens that were subjected to histopathological examination and retrospectively examined. Data from 8,168 specimens submitted to histopathological examination were retrieved from the records. A total of 5,368 cases were included. Agreement was defined based on the definition of lesion nature according to its diagnostic category. Sensitivity, specificity, and positive and negative predictive values were calculated for each diagnostic category. The highest rate of agreement was observed for periapical lesions (92.6%), followed by potentially malignant disorders (90.1%) and non-neoplastic proliferative disorders (89.3%). Low rates of histopathological confirmation of the clinical impression were observed for mesenchymal tumors (25.0%) and cysts (44.2%). Sensitivity values were > 0.70 for all lesions, except for cysts (0.51). Specificity was relatively high, ranging from 0.97 to 1.00. The frequency of incomplete biopsy forms ranged from 16.8% (malignant tumors of oral mucosal epithelium) to 51.0% (nonspecific inflammatory reaction). The most frequently completed biopsy forms corresponded to epithelial malignant tumors (83.2%) and glandular inflammation (72.3%). In conclusion, there was an acceptable level of agreement. The low level of completeness of biopsy forms indicates little awareness about the relevance of gathering detailed information during clinical examination.

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Lack of clinicopathologic correlation in the diagnosis of oral lichen planus based on the presently available diagnostic criteria and suggestions for modifications

Cited by 678 publications

References 18 publications

Squamous cell carcinoma arising in plaque-like oral lichen planus: A case report

Squamous cell carcinoma arising in plaque-like oral lichen planus: A case report

Possible link between Hashimoto's thyroiditis and oral lichen planus: a novel association found

Agreement between clinical and histopathologic diagnoses and completeness of oral biopsy forms

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