Lack of communication about familial colorectal cancer risk associated with colorectal adenomas

Pho, Kevin; Geller, Alan C.; Schroy, Paul C.

doi:10.1016/s0016-5085(00)81509-7

Cited by 9 publications

(12 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Firstly, it is noteworthy that the majority of participants in this study (60%) reported that they have had discussions with their siblings regarding CRC risk, particularly among individuals diagnosed at a younger age. This percentage exceeds those found in prior studies examining whether or not CRC patients disclose their disease status10, 11. CRC patients may serve as a valuable tool for promoting CRC screening.…”

Section: Discussioncontrasting

confidence: 60%

“…Unfortunately, too often, CRC patients do not inform their family members of their own disease status, let alone discuss their increased risk for CRC. Pho and colleagues10 examined communication between CRC patients and their FDRs regarding CRC risk and screening. Less than half (41%) of the patients were aware that their FDRs may be at an increased risk for CRC and among those individuals, only 28% informed relatives of their disease status.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

An Examination of the Psychosocial Factors Influencing Colorectal Cancer Patients' Communication of Colorectal Cancer Patient Risk with Their Siblings

Lawsin

DuHamel

Itzkowitz

et al. 2009

Cancer Epidemiology, Biomarkers &Amp; Prevention

View full text Add to dashboard Cite

This study examined psychosocial factors influencing colorectal cancer (CRC) patients' communication with their first-degree relatives regarding their CRC risk. Among a sample of CRC patients who were members of a colon registry in New York (n = 127), 60% reported discussing CRC risk with their siblings. These discussions were related to the CRC patients' age of diagnosis, such that those diagnosed before age 45 years were more likely to communicate with their siblings about CRC risk. Despite advances made in CRC prevention, compliance with screening recommendations among individuals who may be at familial risk for the disease is low. Perhaps this underrepresentation reflects how CRC patients communicate with their first-degree relatives about their potential risk for the disease. This study examined the psychosocial factors influencing whether CRC patients communicate with their siblings about CRC risk. The sample included CRC patients with siblings who enrolled in a colon disease registry at a NYC metropolitan hospital. Participants completed questionnaires regarding their current psychosocial functioning, perceived risk of sibling's development of CRC, and communication of CRC risk with their siblings. Patients were predominantly Caucasian, with a mean age of 60.4 years. Of the 127 patients, 60% engaged in discussions with their siblings regarding their CRC risk. Patients diagnosed with CRC before the age of 45 years were more likely to discuss the risk of CRC with their siblings (P < 0.01). These data suggest that CRC patients may serve as an effective vehicle to promote CRC screening and support the need for health care providers to not only educate patients of the familial risk of CRC, but to also encourage these patients to communicate this information with their siblings. (Cancer Epidemiol

show abstract

Section: Discussioncontrasting

confidence: 60%

Section: Introductionmentioning

confidence: 99%

An Examination of the Psychosocial Factors Influencing Colorectal Cancer Patients' Communication of Colorectal Cancer Patient Risk with Their Siblings

Lawsin

DuHamel

Itzkowitz

et al. 2009

Cancer Epidemiology, Biomarkers &Amp; Prevention

View full text Add to dashboard Cite

show abstract

“…It has also been observed that affected women and FDRs are more likely to anticipate telling female relatives and siblings than male relatives about BRCA1/2 genetic testing (Julian-Reynier et al, 2000). Not informing relatives of their genetic risk can have negative implications for health where relatives at risk do not engage in appropriate screening (Pho et al, 2000).…”

Section: Seeking and Providing Informationmentioning

confidence: 99%

Juggling roles and expectations: dilemmas faced by women talking to relatives about cancer and genetic testing

Foster

Eeles

Ardern‐Jones

et al. 2004

Psychology & Health

View full text Add to dashboard Cite

Health professionals do not inform their patients' kin about BRCA1/2 test results or genetic testing without their written consent. Thus, the onus is on women attending genetic counselling to talk to relatives about the family history and their potential increased risk. This communication process within the family is largely unexplored and provides the focus of the present study. Fifteen healthy women attending a genetics clinic for predictive testing were interviewed prior to receiving their test result and again 6 months later. A grounded theory approach was used. Findings illustrate the dilemmas women faced in juggling social roles and expectations, which had an impact on communication within the family in the context of predictive genetic testing. Tensions between responsibilities towards themselves and others and their fulfilment of social roles had an impact on who women informed and on how they did so. These factors should be considered when assigning patients the role of information provider.

show abstract

“…Chief among these is the fact that the clinician often cannot communicate directly with at-risk family members and so must transmit complex genetic information and recommendations through the patient. Research on high risk breast and colon cancer cases and their first-degree relatives (FDRs) has found that communication about risk does not flow seamlessly among family members 28,29 and often does not motivate clinical screening or genetic testing. 30 In cardiomyopathies, retrospective single-center studies of mostly hypertrophic cardiomyopathy cases have also demonstrated incomplete uptake of genetic counseling (40%), genetic testing (39-51%) and cardiovascular screening (76%) among FDRs for whom these interventions are indicated.…”

Section: Introductionmentioning

confidence: 99%

Toward Genetics-Driven Early Intervention in Dilated Cardiomyopathy

Kinnamon¹,

Morales²,

Bowen³

et al. 2017

Circ Cardiovasc Genet

View full text Add to dashboard Cite

Background The etiology of idiopathic dilated cardiomyopathy (DCM) is unknown by definition, but its familial subtype is considered to have a genetic component. We hypothesize that most idiopathic DCM, whether familial or non-familial, has a genetic basis, in which case a genetics-driven approach to identifying at-risk family members for clinical screening and early intervention could reduce morbidity and mortality. Methods Based on this hypothesis, we have launched the NHLBI- and NHGRI-funded DCM Precision Medicine Study, which aims to enroll 1,300 individuals (600 non-Hispanic African ancestry, 600 non-Hispanic European ancestry, and 100 Hispanic) who meet rigorous clinical criteria for idiopathic DCM along with 2,600 of their relatives. Enrolled relatives will undergo clinical cardiovascular screening to identify asymptomatic disease, and all individuals with idiopathic DCM will undergo exome sequencing to identify relevant variants in genes previously implicated in DCM. Results will be returned by genetic counselors 12-14 months after enrollment. The data obtained will be used to describe the prevalence of familial DCM among idiopathic DCM cases and the genetic architecture of idiopathic DCM in multiple ethnicity-ancestry groups. We will also conduct a randomized controlled trial to test the effectiveness of Family Heart Talk, an intervention to aid family communication, for improving uptake of preventive screening and surveillance in at-risk first-degree relatives. Conclusions We anticipate this study will demonstrate that idiopathic DCM has a genetic basis and guide best practices for a genetics-driven approach to early intervention in at-risk relatives.

show abstract

Lack of communication about familial colorectal cancer risk associated with colorectal adenomas

Cited by 9 publications

References 0 publications

An Examination of the Psychosocial Factors Influencing Colorectal Cancer Patients' Communication of Colorectal Cancer Patient Risk with Their Siblings

An Examination of the Psychosocial Factors Influencing Colorectal Cancer Patients' Communication of Colorectal Cancer Patient Risk with Their Siblings

Juggling roles and expectations: dilemmas faced by women talking to relatives about cancer and genetic testing

Toward Genetics-Driven Early Intervention in Dilated Cardiomyopathy

Contact Info

Product

Resources

About