2024
DOI: 10.1101/2024.10.10.617409
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Lack of evidence for the contribution of cone photoreceptors to human melatonin suppression and alerting response to light at night

Fatemeh Fazlali,
Rafael Lazar,
Faady Yahya
et al.

Abstract: Light exposure at night can suppress melatonin production and increase alertness, primarily through the action of melanopsin-containing intrinsically photosensitive retinal ganglion cells (ipRGCs). This study investigated whether cone photoreceptors also influence melatonin suppression and subjective alertness using non-visual metameric light emitted from a display. Forty-eight participants with normal trichromatic vision were exposed to three lighting conditions: a baseline (9 lxmEDI), constant background (14… Show more

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