Lack of expression of bundle-forming pili in some clinical isolates of enteropathogenic<i>Escherichia coli</i>(EPEC) is due to a conserved large deletion in the<i>bfp</i>operon

Bortolini, Mafalda R.; Trabulsi, L. R.; Keller, Rogéria; Frankel, Gad; Sperandio, Vanessa

doi:10.1111/j.1574-6968.1999.tb08723.x

Cited by 28 publications

(9 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…These strains were negative for EAF and bfpA probes, but they were positive for perA , an EAF gene [21]. Therefore, like some other atypical strains that have been described in the literature [28-30], these strains carry vestiges of the EAF plasmid.…”

Section: Resultsmentioning

confidence: 99%

Genetic elements associated with antimicrobial resistance in enteropathogenic Escherichia coli (EPEC) from Brazil

et al. 2010

View full text Add to dashboard Cite

BackgroundWe recently observed an association of resistance with a certain enteropathogenic Escherichia coli (EPEC) serotypes and identified a conjugative plasmid, similar to plasmid pED208, that was conserved among archival O111:H2/NM and O119:H2 strains of diverse geographical origin. In this study, we sought to determine the prevalence and distribution of this plasmid among a collection of EPEC isolates from Brazil, as well as to study the susceptibilities of these isolates to antimicrobial agents.ResultsResistance was more commonly seen in typical EPEC than atypical strains. The most prevalent resistances were to ampicillin, tetracycline, streptomycin and the sulfonamides. Markers for the EPEC conjugative multiresistance plasmid, were detected in 21 (30%) of typical but only 4 (5%) of atypical strains (p = 0.001, Chi-squared test). This plasmid, previously reported from only O111 and O119 strains was found in O55 and O127 strains and was associated with the presence of class 1 integrons.ConclusionOur data suggest a limited but expanding host range for the EPEC resistance plasmid.

show abstract

Section: Resultsmentioning

confidence: 99%

Genetic elements associated with antimicrobial resistance in enteropathogenic Escherichia coli (EPEC) from Brazil

et al. 2010

View full text Add to dashboard Cite

show abstract

“…It is important to point out that EPEC strains of serotypes O128:H2 and O119:H2 contain a pEAF with defective bfp operons, which contain part of the bfpA gene but have the rest of the bfp gene cluster deleted. Thus, they are classified as aEPEC 12, 75. Most aEPEC produce adherence patterns categorized as LA-like, with loosened microcolonies compared to those of the tEPEC LA pattern 12, 76, 77.…”

Section: Typical and Atypical Enteropathogenic E Colimentioning

confidence: 99%

Diarrheagenic Escherichia coli

Gomes

Elias

Scaletsky

et al. 2016

Brazilian Journal of Microbiology

432

353

View full text Add to dashboard Cite

Most Escherichia coli strains live harmlessly in the intestines and rarely cause disease in healthy individuals. Nonetheless, a number of pathogenic strains can cause diarrhea or extraintestinal diseases both in healthy and immunocompromised individuals. Diarrheal illnesses are a severe public health problem and a major cause of morbidity and mortality in infants and young children, especially in developing countries. E. coli strains that cause diarrhea have evolved by acquiring, through horizontal gene transfer, a particular set of characteristics that have successfully persisted in the host. According to the group of virulence determinants acquired, specific combinations were formed determining the currently known E. coli pathotypes, which are collectively known as diarrheagenic E. coli. In this review, we have gathered information on current definitions, serotypes, lineages, virulence mechanisms, epidemiology, and diagnosis of the major diarrheagenic E. coli pathotypes.

show abstract

“…For example, serotypes O119:H2 and O128:H2 react with the bfpA probe but do not have a true EAF plasmid. These serotypes have a 100-MDa plasmid that does not contain the bfp operon and consequently does not produce BFP ( 19 ). In contrast, some O142:H6 strains do not react with the EAF probe but produce BFP and show a typical localized adherence (LA) pattern.…”

Section: Serotypesmentioning

confidence: 99%

Typical and Atypical EnteropathogenicEscherichia coli

Trabulsi

Keller

Gomes

2002

Emerg. Infect. Dis.

642

723

View full text Add to dashboard Cite

Typical and atypical enteropathogenic Escherichia coli (EPEC) strains differ in several characteristics. Typical EPEC, a leading cause of infantile diarrhea in developing countries, is rare in industrialized countries, where atypical EPEC seems to be a more important cause of diarrhea. For typical EPEC, the only reservoir is humans; for atypical EPEC, both animals and humans can be reservoirs. Typical and atypical EPEC also differ in genetic characteristics, serotypes, and virulence properties. Atypical EPEC is more closely related to Shiga toxin–producing E. coli (STEC), and like STEC these strains appear to be emerging pathogens.

show abstract

Lack of expression of bundle-forming pili in some clinical isolates of enteropathogenicEscherichia coli(EPEC) is due to a conserved large deletion in thebfpoperon

Cited by 28 publications

References 20 publications

Genetic elements associated with antimicrobial resistance in enteropathogenic Escherichia coli (EPEC) from Brazil

Genetic elements associated with antimicrobial resistance in enteropathogenic Escherichia coli (EPEC) from Brazil

Diarrheagenic Escherichia coli

Typical and Atypical EnteropathogenicEscherichia coli

Contact Info

Product

Resources

About