Lack of postmortem digestion of tapeworms in golden hamsters experimentally infected with Taenia solium

Garza-Rodriguez, Adriana; Maravilla, Pablo; Mendlovic, Fela; Mata-Miranda, Pilar; Robert, Lilia; Flisser, Ana

doi:10.1016/j.vetpar.2006.11.011

Cited by 1 publication

(1 citation statement)

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“…Worms could be identified even at 96 hours post-mortem although damage increased over time. The results obtained indicate that the absence of tapeworms in the human intestine during necropsy is not due to post-mortem digestion, and supports the view that the existing assumptions about the longevity of T. solium may be incorrect (Garza-Rodriguez et al 2007).…”

Section: Tapeworm Survivalsupporting

confidence: 82%

Taenia solium: current understanding of laboratory animal models of taeniosis

et al. 2010

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Neurocysticercosis is a public health problem in many developing countries and is the most frequent parasitic disease of the brain. The human tapeworm carrier is the main risk factor for acquiring neurocysticercosis. Since the parasite lodges only in the human intestine, experimental models of Taenia solium taeniosis have been explored. Macaques, pigs, dogs, cats and rabbits are unsuccessful hosts even in immunodepressed status. By contrast, rodents are adequate hosts since tapeworms with mature, pregravid and, in some cases, gravid proglottids develop after infection. In this review, information that has been generated with experimental models of taeniosis due to T. solium is discussed. Initially, the use of the model for immunodiagnosis of human taeniosis and evaluation of intervention measures is summarized. Next, descriptions of tapeworms and comparison of hamsters, gerbils and other mammals as experimental models are discussed, as well as data on the humoral immune response, the inflammatory reaction and the production of cytokines associated to Th1 and Th2 responses in the intestinal mucosa. Finally, evaluation of protection induced against the development of tapeworms by recombinant T. solium calreticulin in hamsters is summarized and compared to other studies.

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Section: Tapeworm Survivalsupporting

confidence: 82%