Lacrimal fossa lesions: a review of 146 cases in Egypt

Abstract

PurposeThe incidence and clinical and imaging criteria of different pathological forms of lacrimal fossa lesions in the Delta region of Egypt were studied.MethodsA retrospective study of patients with lacrimal fossa lesions for the past 10 years was conducted. A total of 146 cases were identified. Their medical records were reviewed for clinical and imaging data (computed tomography scan, magnetic resonance imaging scan, or both). A definitive diagnosis based on pathological examination of biopsies was also reviewed.ResultsAmong the patients reviewed, 43.15% had inflammatory lacrimal gland lesions, 26.71% had lymphoproliferative lesions, and 21.92% had epithelial lesions; 8.22% had rare lesions (5.48% were dacryops and 2.74% had hemangioma). The study included 71.92% benign lesions and 28.08% malignant lesions, which were distributed between 19.18% malignant lymphoma and 8.9% malignant epithelial tumors. According to the pathological origin of the lesions, they may be classified into 78.08% nonepithelial lesions and 21.92% epithelial lesions (16.44% epithelial tumors, and 5.48% dermoid cysts).ConclusionLacrimal fossa lesions show a wide pathological range. Inflammatory lesions are most frequent, followed by lymphoproliferative and epithelial lesions. Analysis of clinical and radiological criteria is helpful in the differential diagnosis of lacrimal gland lesions.

Lacrimal gland biopsies—results from a tertiary centre in the UK

“…Our study's aim was to investigate the types of pathology that required an incisional or excisional lacrimal gland biopsy. Like other studies, it confirms that the majority of the biopsied specimens were of non-epithelial origin (see Table 2) [1][2][3][4][5][6][7][8][9][10][11][12].…”

Proptosis Revealing a Rare Lacrimal Gland Tumor: A Case of Chondroid Syringoma in a 35-year-old Patient

“… 1 Histologically the most frequent lacrimal gland lesions are inflammatory, lymphoproliferative and epithelial respectively. 2 - 4 Pleomorphic adenoma is the main epithelial tumor of the lacrimal gland. 3 - 5 Pleomorphic adenoma is a well known benign tumor commonly found in salivary glands, however it can be found elsewhere with different names: mixed benign tumor or chondroid syringoma especially in sweat glands.…”

“… 2 - 4 Pleomorphic adenoma is the main epithelial tumor of the lacrimal gland. 3 - 5 Pleomorphic adenoma is a well known benign tumor commonly found in salivary glands, however it can be found elsewhere with different names: mixed benign tumor or chondroid syringoma especially in sweat glands. 6 - 8 Lacrimal gland chondroid syringoma (LGCS) is a very rare tumor with some characteristic clinico-radiological features that could be used for appropriate patient’s management as this neoplasm has potential for recurrence and malignant transformation.…”