Lactobacillus acidophilus Sepsis in a Neonate

Thompson, Charles A.; McCarter, Yvette S.; Krause, Peter J.; Herson, Victor

doi:10.1038/sj.jp.7200509

Cited by 70 publications

(26 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Cases of serious infection have occurred and been reported in the literature. 10,[118][119][120][121][122][123][124][125] Patients at risk would be those who are immunocompromised, including ill preterm neonates, and/or children who have intravenous catheters or other indwelling medical devices. In most cases, the offending organism that caused the sepsis seems to have stemmed from bacteria from the individual's own endogenous flora.…”

Section: Safety Of Probiotics and Prebiotics In Infants And Childrenmentioning

confidence: 99%

Probiotics and Prebiotics in Pediatrics

Thomas¹,

Greer²

2010

Pediatrics

357

220

View full text Add to dashboard Cite

This clinical report reviews the currently known health benefits of probiotic and prebiotic products, including those added to commercially available infant formula and other food products for use in children. Probiotics are supplements or foods that contain viable microorganisms that cause alterations of the microflora of the host. Use of probiotics has been shown to be modestly effective in randomized clinical trials (RCTs) in (1) treating acute viral gastroenteritis in healthy children; and (2) preventing antibiotic-associated diarrhea in healthy children. There is some evidence that probiotics prevent necrotizing enterocolitis in very low birth weight infants (birth weight between 1000 and 1500 g), but more studies are needed. The results of RCTs in which probiotics were used to treat childhood Helicobacter pylori gastritis, irritable bowel syndrome, chronic ulcerative colitis, and infantile colic, as well as in preventing childhood atopy, although encouraging, are preliminary and require further confirmation. Probiotics have not been proven to be beneficial in treating or preventing human cancers or in treating children with Crohn disease. There are also safety concerns with the use of probiotics in infants and children who are immunocompromised, chronically debilitated, or seriously ill with indwelling medical devices. Prebiotics are supplements or foods that contain a nondigestible food ingredient that selectively stimulates the favorable growth and/or activity of indigenous probiotic bacteria. Human milk contains substantial quantities of prebiotics. There is a paucity of RCTs examining prebiotics in children, although there may be some long-term benefit of prebiotics for the prevention of atopic eczema and common infections in healthy infants. Confirmatory well-designed clinical research studies are necessary.

show abstract

Section: Safety Of Probiotics and Prebiotics In Infants And Childrenmentioning

confidence: 99%

Probiotics and Prebiotics in Pediatrics

Thomas¹,

Greer²

2010

Pediatrics

357

220

View full text Add to dashboard Cite

show abstract

“…Cultured from blood stream using sterile technique, Lactobacillus should be recognized as a serious pathogen regardless of mild clinical and laboratory findings, especially in extremely preterm infants [2,3]. We can speculate about different outcome in our patients if the optimal antibiotic treatment was not given.…”

mentioning

confidence: 84%

Congenital Lactobacillus Blood Stream Infection in Extremely Preterm Twins

2016

View full text Add to dashboard Cite

“…Препараты-пробиотики считаются высоко безопас-ными, они редко вызывают негрубые побочные эффекты, чаще всего метеоризм [95]. Тем не менее у иммуноком-прометированных пациентов (в т. ч. у новорожденных детей) в редких случаях они могут быть этиологическим фактором инфекционно-воспалительных процессов [94].…”

Section: различия микробиоты у младенцев находящихся на грудном или unclassified