Lactogenic immunity following vaccination of cattle with bovine coronavirus

Crouch, Colin; Oliver, Stefan L.; Hearle, D.C; Buckley, Alexandra; Chapman, A.; Francis, Michael J.

doi:10.1016/s0264-410x(00)00177-8

Cited by 26 publications

(20 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…46,87 In one study involving 132 cows and heifers with no previous BCoV vaccination history, all were found to have substantial levels of antibodies. 90 In nonvaccinated cows, the rate of virus excretion has been reported to increase by 50% to 60% during the winter months, by 65% at parturition, and by 71% 2 weeks postpartum. 44 This virus is more stable in the colder climates, due to lower ambient temperature and reduced ultraviolet light levels, 47 and has been reported to cause winter dysentery in adult cattle 91 especially after snow storms or sudden changes in ambient temperatures.…”

Section: Pathogenesis and Pathologymentioning

confidence: 99%

“…Protection relies on continual presence of a protective antibody within the gut lumen, which is passively acquired from the dam in the form of specific neutralizing antibodies (predominantly immunoglobulin type 1 [IgG1]) ingested in the colostrum or milk. 78,90 This IgG isotype has activity against the spike protein of BCoV.…”

Section: Strategy For Control and Prevention Of Bovine Coronavirusmentioning

confidence: 99%

See 1 more Smart Citation

Bovine Coronavirus Associated Syndromes

Boileau

Kapil

2010

Veterinary Clinics of North America: Food Animal Practice

133

184

View full text Add to dashboard Cite

Bovine coronaviruses, like other animal coronaviruses, have a predilection for intestinal and respiratory tracts. The viruses responsible for enteric and respiratory symptoms are closely related antigenically and genetically. Only 4 bovine coronavirus isolates have been completely sequenced and thus, the information about the genetics of the virus is still limited. This article reviews the clinical syndromes associated with bovine coronavirus, including pneumonia in calves and adult cattle, calf diarrhea, and winter dysentery; diagnostic methods; prevention using vaccination; and treatment, with adjunctive immunotherapy.

show abstract

Section: Pathogenesis and Pathologymentioning

confidence: 99%

Section: Strategy For Control and Prevention Of Bovine Coronavirusmentioning

confidence: 99%

Bovine Coronavirus Associated Syndromes

Boileau

Kapil

2010

Veterinary Clinics of North America: Food Animal Practice

133

184

View full text Add to dashboard Cite

show abstract

“…This virus is more active in the colder climates and has been reported to cause winter dysentery in adult cattle [16,27]. Control of coronavirus (and rotavirus) infections in calves relies on continual presence of a protective antibody within the gut lumen, which can be achieved by allowing neonates to ingest colostrum or milk containing these specific antibodies from their dams (lactogenic immunity) [19].…”

Section: Coronavirusmentioning

confidence: 99%

Biosecurity for neonatal gastrointestinal diseases

Barrington

Evermann²

2002

Veterinary Clinics of North America: Food Animal Practice

117

143

View full text Add to dashboard Cite

Infectious diarrhea is an important cause of neonatal calf morbidity and mortality that results in significant economic losses in the beef and dairy industries. Although numerous risk factors related to the occurrence of neonatal diarrhea have been identified, they can all be categorized into those that are related to the calf, the pathogens involved, or the environment of the calf. The immune status of calves, specifically the level of passively acquired immunity through colostrum, is the major risk factor related to the calf and the occurrence of diarrhea. Although numerous pathogens have been implicated in the occurrence of neonatal diarrhea, only a relatively limited number are commonly involved. Most should be viewed as secondary opportunists rather than primary pathogens, because none are extraordinarily virulent, and with the exception of Salmonella spp., most are present within the gastrointestinal tract of many healthy, mature cattle. Important risk factors related to pathogens involved in neonatal calf diarrhea involve the size of the inoculum and the occurrence of multiple infections. Finally, when considering the environment and housing conditions in which beef and dairy calves may reside, it is clear that tremendous variations exist. Despite these variations, the risk factors associated with the environment of the calf are also those that are the most amenable to the implementation of general environmental control and monitoring strategies as well as specific biosecurity measures.

show abstract

“…Disease outcomes' induced by BCoV are responsible for significant economical losses to beef and dairy industries worldwide. These losses are not only the figure of mortalities, which may reach 80% in some complicated cases, but also reflect the veterinary costs, medications and poor productivity of affected animals [4].…”

Section: Introductionmentioning

confidence: 99%

Development of a SYBR Green I based real-time RT-PCR assay for detection and quantification of bovine coronavirus

Amer

Almajhdi

2011

Molecular and Cellular Probes

View full text Add to dashboard Cite

A novel two-step, SYBR Green I based real-time RT-PCR assay was developed for detection and quantification of BCoV using ABI PRISM 7500 sequence detection system. The assay was carried out using two sets of primers designed to amplify highly conserved sequences of the nucleocapsid gene of BCoV and the internal control, bovine glyceraldehyde-3-phosphate dehydrogenase, RNA. Specific identification of both targets was elucidated by melt curve analysis, in which the BCoV amplified product generated a melt peak at 78.35 ± 0.26 °C and the internal control RNA at 82.54 ± 0.32 °C. The assay was highly specific since all negative controls and other viruses of clinical and structural relevance failed to develop any positive results. The detection limit of the reaction was 10(3) plasmid copies and 1.17 × 10(-3) TCID(50) of the tissue culture propagated virus. Standard deviation and coefficient of variation was low for both intra-assay and inter-assay variability. The assay performance on field samples was evaluated on 103 (68 fecal and 35 nasal) swab specimens and compared with the conventional RT-PCR assay. The results of both assays matched for the diagnosis of 65 fecal and 33 nasal samples. However, three fecal and two nasal samples tested negative in gel-based assay were positive for the real-time RT-PCR. The robustness and a high-throughput performance of the developed assay make it a powerful tool in diagnostic applications and in BCoV research.

show abstract

Lactogenic immunity following vaccination of cattle with bovine coronavirus

Cited by 26 publications

References 11 publications

Bovine Coronavirus Associated Syndromes

Bovine Coronavirus Associated Syndromes

Biosecurity for neonatal gastrointestinal diseases

Development of a SYBR Green I based real-time RT-PCR assay for detection and quantification of bovine coronavirus

Contact Info

Product

Resources

About