Lactose Intolerance

Jansson-Knodell, Claire; Krajicek, Edward; Savaiano, Dennis; Shin, Andrea

doi:10.1016/j.mayocp.2020.04.036

Cited by 26 publications

(13 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Lactose intolerance is prevalent in 15% of Caucasians, 53% of Hispanics, 80% with African ancestry, 70% Asian Indian, and 90% of Chinese descent [23][24], and globally is the commonest cause of food intolerance. Alterations in the LCT gene is considered the most likely explanation for lactose intolerance [25]. Mutations in the LCT explain lactase persistence vs. nonpersistence, although genetic coding for lactase nonpersistence do not always correlate with symptoms or test results for lactose intolerance.…”

Section: Prevalence Of Lactose Intolerancementioning

confidence: 99%

Bacterial overgrowth and lactose intolerance: how to best assess

Ghafoor

Karunaratne

Rao

2022

Current Opinion in Clinical Nutrition &Amp; Metabolic Care

View full text Add to dashboard Cite

Purpose of reviewTo provide an up-to-date review on the clinical assessment of two important gastrointestinal problems with overlapping symptomatology but diverse cause and testing methods. Small intestinal bacterial overgrowth (SIBO) is characterized by the presence of excess bacteria in the small intestine associated with bloating, distention, gas, and diarrhea. Lactose intolerance is caused by lactase enzyme deficiency in the small bowel mucosa leading to lactose malabsorption and symptoms of bloating, gas, and diarrhea.Recent findingsSIBO is assessed by hydrogen/methane breath test using glucose as a substrate and/or small bowel aspirate and culture but these tests have shortcomings. Consequently, several new diagnostic techniques, including novel capsule technologies and other approaches are being evaluated. Lactose intolerance can be assessed by hydrogen/methane breath test using lactose as a substrate, or small bowel mucosal lactase assay, genetic testing and lactose tolerance test, although the efficacy and practicality of these diagnostic modalities are not equal.SummaryIn clinical practice, gas, bloating, distention, pain, and diarrhea are common gastrointestinal symptoms that often remain unexplained when routine gastrointestinal endoscopy, imaging, and stool tests are negative. These patients should be evaluated for SIBO and/or food intolerances including lactose intolerance.

show abstract

Section: Prevalence Of Lactose Intolerancementioning

confidence: 99%

Bacterial overgrowth and lactose intolerance: how to best assess

Ghafoor

Karunaratne

Rao

2022

Current Opinion in Clinical Nutrition &Amp; Metabolic Care

View full text Add to dashboard Cite

show abstract

“…Unmetabolized lactose passes into the colon and is fermented by bacteria to products such as short-chain fatty acids, hydrogen (H2), methane (CH4), and carbon dioxide (CO2) gases (Yang et al, 2015). These products cause symptoms such as abdominal pain, flatulence, cramps, bloating, diarrhea, and fatigue that occur within 30 minutes or a few hours after consumption of lactose-containing foods in individuals with LI (Campbell et al, 2010;Kumar, Ranjan, Mittal, Singh, & Ghoshal, 2012;Jansson-Knodell, Krajicek, Savaiano, & Shin, 2020). The main method used in the diagnosis of LI is the hydrogen breath test, which is a non-invasive method that provides objective information about the digestion and absorption of lactose (Yang et al, 2015).…”

Section: Lactose Intolerancementioning

confidence: 99%

Lactose Intolerance and Osteoporosis Development in Irritable Bowel Syndrome Patients

Aycan

PINAR

2022

Bandırma Onyedi Eylül Üniversitesi Sağlık Bilimleri Ve Araştırmaları Dergisi

View full text Add to dashboard Cite

Irritable bowel syndrome (IBS) is one of the most common chronic functional disorders among gastrointestinal system diseases. IBS, which has a high prevalence worldwide, negatively affects the quality of life of patients. The mechanisms that are effective in the development of IBS has not clearly been defined. However, its mechanism is thought to be multifactorial. IBS is characterized by certain symptoms, such as abdominal pain, diarrhea, constipation, flatulence, and indigestion. Nevertheless, these symptoms aren’t specific to IBS and can often be confused with lactose intolerance (LI) symptoms. On the other hand, the probability of having LI at the same time is quite high in IBS patients. IBS patients restrict lactose-containing foods, especially milk and dairy products, due to the thought that they trigger their symptoms, and thus calcium deficiency may occur as a result. Due to insufficient calcium intake for a long time, the risk of osteoporosis and osteoporotic fractures becomes an important problem. In line with all these factors, this review aims to examine osteoporosis that may develop due to the presence of LI in IBS patients and to make nutritional recommendations.

show abstract

“…They also contain carbohydrates, especially in the form of lactose, which might be problematic for some consumers with lactose intolerance. However, people suffering from this pathology, which causes gastrointestinal malfunctioning, do not derive their symptoms exclusively form the consumption of dairy products, contrarily to popular belief, as discussed by Jansson-Knodell et al [13]. Usual gastrointestinal symptoms that can appear after lactose ingestion in individuals with lactose intolerance include abdominal pain, diarrhea, flatulence and bloating [14].…”

Section: Introductionmentioning

confidence: 99%

“…Usual gastrointestinal symptoms that can appear after lactose ingestion in individuals with lactose intolerance include abdominal pain, diarrhea, flatulence and bloating [14]. Some people believe they have lactose intolerance when they in fact have not been diagnosed by a physician, and their gastrointestinal problems are derived from something other than lactose [13,15]. Nevertheless, those individuals who believe themselves to be lactose intolerant or who follow fashionable dietary trends tend to avoid milk and other related dairy products [15][16][17].…”

Section: Introductionmentioning

confidence: 99%

Study of the Influence of Sociodemographic and Lifestyle Factors on Consumption of Dairy Products: Preliminary Study in Portugal and Brazil

Guiné

Florença

Carpes

et al. 2020

Foods

View full text Add to dashboard Cite

Sociodemographic characteristics, including regional variations, have been associated with different food consumption patterns. Behavioral factors and lifestyle variables may also contribute to different food dietary trends. In this way, the present study intended to investigate the consumption habits of the most relevant types of dairy products around the world and relate them to sociodemographic factors, for example, age, sex, education and country as well as with some anthropometric and behavioral aspects, for example, body mass index, satisfaction with body weight and exercise or sedentary lifestyles. One other objective of the study was to categorize the lifestyles of the participants, according to measured variables linked with hours of inactivity or exercise, in order to use these as possible differentiating variables for the consumption of dairy products. The study involved a questionnaire survey undertaken on a non-probabilistic convenience sample of participants from Portugal (PT) and Brazil (BR), and participation was voluntary and anonymous. The data analysis involved different statistical techniques: basic statistics, chi-square tests, factor analysis, cluster analysis and tree classification analysis. The results showed that semi skimmed milk is never consumed by about half of the participants (47.4% for PT and 46.7 for BR), and those numbers increase for skimmed (64.8% for PT and 50.9% for BR), chocolate flavored milk (82.6% for PT and 65.6% for BR) and enriched milks (94.8% for PT and 85.3% for BR). Cheeses are also consumed in the two countries by small numbers of people. The number of participants consuming imported cheeses in both countries was particularly low (only 4.0% consume these more than once a week in both countries), suggesting national products may be preferred. It was further observed that those who consume cheese do it seldom (once a week) or sometimes (2–3 times per week). Butter is also consumed by only about half of the adult population (43.8% for PT and 49.5% for BR), but the percentage of those who never consume butter increases for skimmed butter (66.0% for PT and 82.6% for BR) and unsalted butter (70.2% for PT and 69.1% for BR). The consumption of yogurts also follows similar low consumption patterns. The most frequently consumed yogurt types in Portugal are liquid (30.5% consume regularly) and natural yogurts (34.8% consume regularly), while in Brazil the most frequent are creamy fruit pulp yogurt (14.4% consume regularly), liquid (13.7% consume regularly) and Greek type yogurt (10.2% consume regularly). A factor analysis and a cluster analysis established groups according to lifestyles, as follows: 1—Screeners, 2—Exercisers, 3—Travelers and 4—Others. These lifestyles were found to be influential in the consumption of dairy products for all classes of dairy tested: milk, cheese, yogurt and butter. For example, the screeners were found to consume more milk, more butter, more cheese and more yogurt. Additionally, other influential factors were age, sex, education, BMI and satisfaction with body weight. Nevertheless, country was not a meaningfully discriminant variable in relation to the other variables included in the classification analysis. The results concluded that, despite some small differences in the patterns of consumption of dairy products in both countries, the levels of consumption of dairy products are extremely low, for all classes studied (milk, cheese, yogurt or butter). Additionally, it was concluded that some factors are influential on the level of consumption of dairy products, and therefore decision makers can plan their interventions according to the characteristics of the targeted segments of the population, according to lifestyle, age, sex, education, BMI and satisfaction with body weight.

show abstract

Lactose Intolerance

Cited by 26 publications

References 28 publications

Bacterial overgrowth and lactose intolerance: how to best assess

Bacterial overgrowth and lactose intolerance: how to best assess

Lactose Intolerance and Osteoporosis Development in Irritable Bowel Syndrome Patients

Study of the Influence of Sociodemographic and Lifestyle Factors on Consumption of Dairy Products: Preliminary Study in Portugal and Brazil

Contact Info

Product

Resources

About