A novel implementation of an analogue low-power, second-order, low-pass filter with tunable quality factor (Q) is presented and discussed. The filter feature is a relatively simple, buffer-based, circuit network consisting of eleven transistors operating in a subthreshold region. Q tuning is accomplished by injecting direct current into a network node, which changes the output resistance of the transistors and, as a result, modifies the filter network’s loss, and thus its Q. Q tuning is independent of a filter cut-off frequency (ω0). The filter, with a nominal ω0 of 1 kHz, was fabricated using a 0.18 µm CMOS technology, and features a Q range of 2–11, power consumption of up to 52 nW, and a 59 dB dynamic range when using a 0.5 V supply. The ω0 can be tuned from 0.5 to 2.5 kHz using a traditional method by changing the transistor transconductances, but this process partially affects the quality factor.