2000
DOI: 10.1007/s004150070157
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Lamotrigine in trigeminal neuralgia secondary to multiple sclerosis

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Cited by 74 publications
(31 citation statements)
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“…132 In the second, pain relief was achieved in 16 out of 18 patients. 133 Typically, doses used were up to 400 mg daily. (These two reports are from the same authors, so there may be overlap in the patients included.…”
Section: Lamotriginementioning
confidence: 99%
“…132 In the second, pain relief was achieved in 16 out of 18 patients. 133 Typically, doses used were up to 400 mg daily. (These two reports are from the same authors, so there may be overlap in the patients included.…”
Section: Lamotriginementioning
confidence: 99%
“…It is unknown whether differences in disease mechanism causing nerve pain alter the responsiveness to analgesia. 10 There have been few randomized controlled trials (RCTs) of pharmacotherapeutics for MS pain, and most of those studies have focused on treating trigeminal neuralgia in MS. [11][12][13][14][15] Three RCTs examined the use of cannabinoid derivatives (oral or oropharyngeal spray preparations) for MSrelated pain including dysesthetic limb pain and painful spasms. The studies found some evidence of effectiveness in pain relief, but the utility of these medications is limited by safety concerns, adverse effects, and their status with the Drug Enforcement Agency.…”
Section: Discussionmentioning
confidence: 99%
“…54 Lamotrigine was recently validated for use in refractory trigeminal neuralgia, especially due to multiple sclerosis. 51,52,55 Gabapentin in the Treatment of Periodic Limb Movement Disorder of Sleep Periodic limb movements of sleep occur as an asleep phenomenon and are characterized by periodic episodes of repetitive and highly stereotyped limb movements. These patients typically have complaints of insomnia or excessive sleepiness with no other disorder to explain the symptoms.…”
Section: Gabapentin In the Treatment Of Trigeminal Neuralgiamentioning
confidence: 99%
“…52 Referral to an asthma specialist (usually an allergist or pulmonologist)-particularly for patients with severe asthma-may help improve medical adherence to asthma management guidelines and patient QOL. [53][54][55] Westley et al 56 reviewed the charts of 70 moderate-to-severe asthma patients enrolled in a large staff model HMO before and after referral to an asthma specialist (either allergist or pulmonologist). Following consultation with the specialist, there was a 45% decrease in the number of office visits for asthma, a 55% decrease in acute care visits, a 67% decrease in hospitalizations, and a cost savings of $2,100 per patient.…”
Section: Impact Of Managed Care Interventionmentioning
confidence: 99%