Land governance is a linchpin for sustainable socioeconomic development and the protection of property rights in Ghana. Efficient land resource management is essential for fostering equitable access to land and ensuring the well-being of citizens. This study aims to explore the multifaceted landscape of land governance in Ghana and inform the development of an efficient Land Information System (LIS). Drawing from international perspectives and the legal framework of Ghana, this research unveils the complexities, challenges, and opportunities inherent in the land governance system of the country. The study delves into thirteen (13) key areas requiring attention and improvement, spanning legal frameworks, land surveying, digital technology adoption, decentralization, transparency, capacity building, public awareness, data security, collaboration, customary land systems, conflict resolution, regular updates, and financial sustainability. By dissecting these components, the research highlights the intricate interplay between effective land governance and the role of an efficient LIS. The study provides valuable insights and recommendations for policymakers, government agencies, and stakeholders, with the intent to enhance land governance practices and build effective LIS in Ghana. This study also contributes to the realization of a more transparent, accessible, and equitable land management system that aligns with the development aspirations of the nation. This study also serves as a roadmap for fostering sustainable growth, bolstering land tenure security, and driving positive institutional change in the land governance landscape of Ghana.