We study the influence of topological defects on the spin current as well as the spin Hall effect. We find that the nontrivial deformation of the space time due to topological defects can generate a spin-dependent current which then induces an imbalanced accumulation of spin states on the edges of the sample. The corresponding spin Hall conductivity has also been calculated for the topological defect of a cosmic string. Compared to the ordinary value, a correction which is linear with mass density of the cosmic string appears. Our approach to the dynamics of non relativistic spinor in the presence of a topological defect is based on the Foldy-Wouthuysen transformation. The spin current is obtained by using the extended Drude model which is independent of the scattering mechanism.