Landmarks in BPH—from aetiology to medical and surgical management

Kahokehr, Arman; Gilling, Peter

doi:10.1038/nrurol.2013.318

Cited by 15 publications

(5 citation statements)

References 59 publications

(52 reference statements)

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“…Typically, patients are first treated with oral medications geared toward shrinking the prostate and relaxing the smooth muscle of the bladder neck to facilitate urinary flow 4,5 . Surgical intervention is often warranted in those with LUTS secondary to BPH that is refractory to medical management, with the goal of controlling the symptoms and potential complications of BPH such as urinary retention and recurrent urinary tract infections 6 …”

Section: Introductionmentioning

confidence: 99%

Emerging outcomes of water vapor thermal therapy (Rezum) in a broad range of patients with lower urinary tract symptoms secondary to benign prostatic hyperplasia: A systematic review

Babar

Loloi

Tang

et al. 2022

LUTS

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Water vapor thermal therapy (Rezum) is a novel, minimally invasive surgical technology used to treat lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia (BPH). The objective of this systematic review is to evaluate the latest efficacy and safety profile of Rezum in patients with LUTS secondary to BPH. PubMed/MEDLINE and the Cochrane Library databases were systematically searched, in accordance with the PRISMA statement, for relevant articles in the English language till 1 August 2021. Randomized and nonrandomized studies that evaluated urinary outcomes and/or adverse events were deemed eligible. Nineteen studies (N = 1942), published in 25 articles, were included. International Prostate Symptom Score (IPSS), quality of life (QoL), and maximum urinary flow rate (Qmax) significantly improved as early as 1 month postoperatively and remained durable for up to 5 years. Significant median percent improvements in IPSS, QoL, and Qmax at 3 months were 51%, 51%, and 66%, respectively. Patients with obstructive median lobes, large prostates (>80 g), small prostates (<30 g), and urinary retention also experienced significant relief in LUTS, with 83% of urinary retention patients becoming catheter independent at a median of 14 days. Most adverse events were transient and nonserious and occurred in 0% to 76% of patients (median 29%), with de novo erectile dysfunction rates ranging between 0% and 3.1%. Surgical retreatment rate ranged between 4.4% and 7.5% at 5 years postoperatively. Rezum provides durable improvements in symptoms, irrespective of prostate volume and urinary retention status, and has low rates of sexual dysfunction.

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Section: Introductionmentioning

confidence: 99%

Emerging outcomes of water vapor thermal therapy (Rezum) in a broad range of patients with lower urinary tract symptoms secondary to benign prostatic hyperplasia: A systematic review

Babar

Loloi

Tang

et al. 2022

LUTS

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“…Treatment alternatives for patients with moderate‐to‐severe symptoms of BPH include, but are not limited to, medical management, minimally invasive therapies, and surgical intervention. Surgical intervention options have evolved from electrosurgical resection to the use of lasers for enucleation and ablation . TURP was first performed over 80 years ago and is still regarded as the ‘gold standard’ for the treatment of BPH in prostates between 30 and 80 mL .…”

Section: Introductionmentioning

confidence: 99%

Aquablation – image‐guided robot‐assisted waterjet ablation of the prostate: initial clinical experience

et al. 2015

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These preliminary results from this initial study show aquablation of the prostate is technically feasible with a safety profile comparable to other BPH technologies. The combination of surgical mapping by the operating surgeon and the high-velocity saline provides a promising technique delivering a conformal, quantifiable, and standardised heat-free ablation of the prostate. Advantages of this technique include reduction in resection time compared with other endoscopic methods, as well as the potential to preserve sexual function.

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“…Clinical symptoms of BPH have been described as ‘prostatism’. This terminology was sufficient, but perhaps oversimplified, for another era 6 . However, not all men with histological BPH would develop clinical sequelae.…”

Section: Improvements In Terminologymentioning

confidence: 99%

Recent advances in the understanding of male lower urinary tract symptoms (LUTS)

Kahokehr

Gilling

2016

F1000Res

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Landmarks in BPH—from aetiology to medical and surgical management

Cited by 15 publications

References 59 publications

Emerging outcomes of water vapor thermal therapy (Rezum) in a broad range of patients with lower urinary tract symptoms secondary to benign prostatic hyperplasia: A systematic review

Emerging outcomes of water vapor thermal therapy (Rezum) in a broad range of patients with lower urinary tract symptoms secondary to benign prostatic hyperplasia: A systematic review

Aquablation – image‐guided robot‐assisted waterjet ablation of the prostate: initial clinical experience

Recent advances in the understanding of male lower urinary tract symptoms (LUTS)

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