2023
DOI: 10.1186/s12967-023-04787-z
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Landscape of molecular crosstalk between SARS-CoV-2 infection and cardiovascular diseases: emphasis on mitochondrial dysfunction and immune-inflammation

Shiyu Dai,
Ting Cao,
Han Shen
et al.

Abstract: Background SARS-CoV-2, the pathogen of COVID-19, is a worldwide threat to human health and causes a long-term burden on the cardiovascular system. Individuals with pre-existing cardiovascular diseases are at higher risk for SARS-CoV-2 infection and tend to have a worse prognosis. However, the relevance and pathogenic mechanisms between COVID-19 and cardiovascular diseases are not yet completely comprehended. Methods Common differentially expressed … Show more

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Cited by 5 publications
(1 citation statement)
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“…Furthermore, this short treatment period also allowed for the rapid approval of drug trials due to the emergency, life-threatening COVID-19 pandemic conditions [13]. Similar approaches have also been considered for the development of drugs for the treatment of the severe acute respiratory syndrome and other life-threatening side effects of the virus, affecting other systems in addition to the respiratory system, such as the cardiovascular, gastrointestinal, nervous, immune and hematopoietic systems [20][21][22][23][24][25]. A different approach has been considered for the development of other drugs that are related to each of the different stages of COVID-19 and also for the "long COVID" side effects [11,[26][27][28][29][30][31][32][33].…”
mentioning
confidence: 99%
“…Furthermore, this short treatment period also allowed for the rapid approval of drug trials due to the emergency, life-threatening COVID-19 pandemic conditions [13]. Similar approaches have also been considered for the development of drugs for the treatment of the severe acute respiratory syndrome and other life-threatening side effects of the virus, affecting other systems in addition to the respiratory system, such as the cardiovascular, gastrointestinal, nervous, immune and hematopoietic systems [20][21][22][23][24][25]. A different approach has been considered for the development of other drugs that are related to each of the different stages of COVID-19 and also for the "long COVID" side effects [11,[26][27][28][29][30][31][32][33].…”
mentioning
confidence: 99%