The purpose of the study is to implement a new model based on the Navier-Stokes equations for the characterization of landslide sediments interacting with a moving fluid. The model is implemented by combining Hypermesh, the LS-DYNA software and MATLAB. The results show that the main factors affecting the permeability of landslide sediments are the genetic mechanism, the structure and composition of materials, material lithology, and stress. The characteristics and mechanism of permeability changes are determined by adjusting the water levels of fluids. It is found that the permeability of landslide sediments increases at the front and decreases in the middle and at the rear of the considered domain. The magnitude of the internal flow for the whole system decreases first and then increases with a change in the water level during seepage.