Langerhans cell histiocytosis

Aruna, D R; Pushpalatha, G; Galgali, Sushma Ravindra; Prashanthy,

doi:10.4103/0972-124x.85675

Cited by 16 publications

(12 citation statements)

References 7 publications

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“…Hashimoto Pritzker syndrome is a congenital form of LCH presenting with a deep subcutaneous skin lesions. [ 4 6 ] Solitary type of eosinophilic granuloma is twice as common as multiple variants and is most common among other three variants. In the present case, the patient exhibited a solitary skeletal lesion with no extraskeletal involvement hence was considered as eosinophilic granuloma variant.…”

Section: Discussionmentioning

confidence: 99%

Langerhans cell histiocytosis revisited: Case report with review

et al. 2015

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Langerhans cell histiocytosis (LCH) is a group of idiopathic disorders characterized by proliferation of bone marrow derived Langerhans cells and mature eosinophils. Their clinical features simulate common oral findings such as gingival enlargement, oral ulcers, and mobility of teeth, along with nonspecific radiographic features; hence, diagnosing such lesions becomes difficult for the oral physicians. These lesions are commonly seen in childhood; however, we are reporting a case of LCH in 29-year-old adult male. A provisional diagnosis of giant cell granuloma was considered based on history and examination, although the lesion was histologically proven to be LCH and was confirmed with immunohistochemical staining of S100 protein and CD1a antigen. The purpose of this paper is to enhance the understanding of diverse, nonpathognomical oral presentation of LCH that is easily misdiagnosed and overlooked by dentist.

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Section: Discussionmentioning

confidence: 99%

Langerhans cell histiocytosis revisited: Case report with review

et al. 2015

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“…Langerhan’s cell histiocytosis (LCH) involves a rare group of hematological disorders originating from Langerhans cells that may affect the oral cavity [ 54 ]. Periodontal tissues are frequently involved and appear as located or generalized angular bone loss mimicking radiographic characteristics of an advanced periodontitis, such also is found in SOT [ 2 , 4 , 6 , 7 , 9 - 20 , 54 , 55 ]. Therefore, LCH and SOT should be considered as differential diagnosis when a severe periodontitis is present in the x-ray findings and no improvement is reached after periodontal treatment.…”

Section: Literature Reviewmentioning

confidence: 99%

Squamous Odontogenic Tumor: Literature Review Focusing on the Radiographic Features and Differential Diagnosis

Mardones

Gamba

Flores

et al. 2015

TODENTJ

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Since its first publication in 1975, the squamous odontogenic tumor remains the rarest odontogenic lesion, with around 50 cases in the English-language literature in which the microscopic characteristics are frequently very well demonstrated. However, articles which discuss the radiographic aspects are scarce, especially with emphasis on the differential diagnosis. The present treatise proposes an assessment of jaw lesions with the same radiographic characteristics of the squamous odontogenic tumor to clarify the main findings for dental clinicians during routine diagnosis.

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“…Hashimoto–Pritzker syndrome is a congenital form of LCH presenting with deep subcutaneous skin lesions. [910] In the present case, the patient exhibited a multiple skeletal lesion with no extraskeletal involvement; hence, it was considered as eosinophilic granuloma.…”

Section: Discussionmentioning

confidence: 90%

A rare and unusual case report of Langerhans cell histiocytosis

Rao¹,

Trivedi²,

Havale³

et al. 2017

J Oral Maxillofac Pathol

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Langerhans cell histiocytosis (LCH), previously known as histiocytosis X, is an uncommon hematological disorder affecting infants and young children. It is the condition characterized by uncontrolled stimulation and proliferation of normal antigen presenting cells, Langerhans cells. Because of its relatively low incidence, limited data are available regarding the epidemiology of LCH, with estimation of 2–5 cases per million inhabitants per year. The purpose of this report is to describe the case of LCH in the 3-year-old male child with multiple focal involvements of bones and to discuss clinical, radiological and histopathological features of LCH and role of the dental surgeon in diagnosing and managing such lesions.

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Langerhans cell histiocytosis

Cited by 16 publications

References 7 publications

Langerhans cell histiocytosis revisited: Case report with review

Langerhans cell histiocytosis revisited: Case report with review

Squamous Odontogenic Tumor: Literature Review Focusing on the Radiographic Features and Differential Diagnosis

A rare and unusual case report of Langerhans cell histiocytosis

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