Langmuir and Langmuir–Blodgett technologies as nanoarchitectonic tools for the incorporation of curcumin in membrane systems

Abstract

Thermodynamic studies of Langmuir model cell membranes oriented to the rational design of lipid formulations.

Exploring the Use of a Lipopeptide in Dipalmitoylphosphatidylcholine Monolayers for Enhanced Detection of Glyphosate in Aqueous Environments

“…By examining Langmuir monolayers, we assessed the impact of varying lipopeptide (LP) concentrations on phosphatidylcholine (PC) within the lipid membrane. The molecular area-pressure isotherm for the pure PC monolayer displays characteristic behavior, as documented in the literature. − With increased LP concentration within the lipid monolayer, we note a decrease in the average molecular area and a reduction in maximum surface pressure (Figure A). This observation aligns with the properties of LP, which, as a single-chain molecule, occupies a smaller molecular area than pure PC …”

“…Phosphatidylcholine (PC) forms a more rigid structure than other compositions, as depicted in Figure S4. We identify the expanded liquid (LE) phase in the range of 12.5 < C S –1 < 50 mN/m and the condensed liquid (LC) phase within 100 < C S –1 < 250 mN/m, which are characteristic of a pure PC monolayer . Incorporating lipopeptides (LPs) into the monolayer results in a notable reduction in C S –1 values, reaching approximately 60 mN/m, indicative of the LE phase (Figure S4).…”

Influence of the Type of Biocompatible Polymer in the Shell of Magnetite Nanoparticles on Their Interaction with DPPC in Two-Component Langmuir Monolayers

“…For this reason, complementary methods based on model cell membranes, which allow to investigate interactions between nanomaterials and phospholipids at the molecular level, have attracted much attention . A Langmuir technique is one of the well-known and widely applied methods for the preparation of model cell membranes. − This technique has also been successfully used in studies of interactions between different nanoparticles and phospholipids, including MNPs. − A single Langmuir monolayer formed from phospholipids can be considered as an oversimplified experimental model of a cell membrane consisting of two weakly coupled monolayers, which is a complex and dynamic system. The composition of a model membrane can be precisely designed with the Langmuir method, which allows the formation of one- or multi-component monolayers from different types of phospholipids and other components of membranes.…”

Molecular Templates on Surfaces by Exploiting Supramolecular Chemistry in Langmuir–Blodgett Monolayers

“…This level of control reached by nanoarchitectonic tools finds extensive applications across various domains, spanning from the production of (bio)sensors to the capture and containment of greenhouse gases, extending its influence into DNA sequencing, nanoreactors, photovoltaic and thermoelectric cells, as well as nanoelectronics, spintronics, quantum computing, molecular (thermo)electronic devices, among a plethora of others. [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17] For these reasons, the assembly of thin templates on surfaces has gained significant attention due to its key role in directing the organization of functional materials, opening the path toward the fabrication of assemblies that integrate a precise number of molecules in specific locations or even arrays of unimolecular devices. While molecular networks have been reported previously in the literature, initially their preparation often required methodologies involving the sublimation of the molecular material within high vacuum systems.…”

“…This level of control reached by nanoarchitectonic tools finds extensive applications across various domains, spanning from the production of (bio)sensors to the capture and containment of greenhouse gases, extending its influence into DNA sequencing, nanoreactors, photovoltaic and thermoelectric cells, as well as nanoelectronics, spintronics, quantum computing, molecular (thermo)electronic devices, among a plethora of others. [ 1–17 ]…”