Language Growth in Young Children with Autism: Interactions Between Language Production and Social Communication

Blume, Jessica; Wittke, Kacie; Naigles, Letitia R.; Mastergeorge, Ann M.

doi:10.1007/s10803-020-04576-3

Cited by 31 publications

(24 citation statements)

References 136 publications

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“…On the other hand, patients classified as having high functioning autism had an incidence of only 20% of these anomalies. The fact that these patients, unlike other autistic patients, achieve good language skills, suggests that epileptiform abnormalities could have a negative effect on language development or could reflect a severer brain dysfunction, which affects language and neuronal excitability [ 23 , 43 , 44 , 45 ]. Moreover, patients with autism and severe intellectual disability had a higher rate of EEG abnormalities ( p = 0.03) compared to patients with autism and mild, moderate or without intellectual disability.…”

Section: Seas In Non-epileptic Patients With Asdmentioning

confidence: 99%

Electroencephalographic Abnormalities in Autism Spectrum Disorder: Characteristics and Therapeutic Implications

et al. 2020

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A large body of literature reports the higher prevalence of epilepsy in subjects with Autism Spectrum Disorder (ASD) compared to the general population. Similarly, several studies report an increased rate of Subclinical Electroencephalographic Abnormalities (SEAs) in seizure-free patients with ASD rather than healthy controls, although with varying percentages. SEAs include both several epileptiform discharges and different non-epileptiform electroencephalographic abnormalities. They are more frequently associated with lower intellectual functioning, more serious dysfunctional behaviors, and they are often sign of severer forms of autism. However, SEAs clinical implications remain controversial, and they could represent an epiphenomenon of the neurochemical alterations of autism etiology. This paper provides an overview of the major research findings with two main purposes: to better delineate the state-of-the-art about EEG abnormalities in ASD and to find evidence for or against appropriateness of SEAs pharmacological treatment in ASD.

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Section: Seas In Non-epileptic Patients With Asdmentioning

confidence: 99%

Electroencephalographic Abnormalities in Autism Spectrum Disorder: Characteristics and Therapeutic Implications

et al. 2020

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“…The current review focused on lexical knowledge and excluded studies on lexical learning. Previous studies found that the word learning mechanisms of children with ASD may be different and widely affected by their social difficulties (see Abdelaziz et al, 2018;Blume et al, 2021;Kelty-Stephen et al, 2020). The fact that some studies reported that the children with ASD displayed odd behavioral patterns, different from those observed in TD (and other clinical) groups, calls for more studies to assess whether lexical semantic development may be different, even in children for whom it does not seem delayed.…”

Section: Discussionmentioning

confidence: 99%

Lexical Semantic Knowledge of Children with ASD—a Review Study

Sukenik

Tuller

2021

Rev J Autism Dev Disord

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Studies on the lexical semantic abilities of children with autism have yielded contradicting results. The aim of the current review was to explore studies that have specifically focused on the lexical semantic abilities of children with ASD and try to find an explanation for these contradictions. In the 32 studies reviewed, no single factor was found to affect lexical semantic skills, although children with broader linguistic impairment generally, but not universally, also showed impaired lexical semantic skills. The need for future studies with young ASD participants, with differing intellectual functioning, longitudinal studies, and studies assessing a wide range of language domains are discussed.

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“…In particular, fractional anisotropy in the occipital region of the ILF was correlated with language ability, but not ADOS severity scores. Other efforts utilizing the APP have identified subgroups based interactions between social communication and language development ( Blume et al, 2021 ) and grammatical language ability ( Wittke et al, 2017 ).…”

Section: Subgrouping By Behavioral and Clinical Characteristicsmentioning

confidence: 99%

The Autism Phenome Project: Toward Identifying Clinically Meaningful Subgroups of Autism

et al. 2022

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One of the most universally accepted facts about autism is that it is heterogenous. Individuals diagnosed with autism spectrum disorder have a wide range of behavioral presentations and a variety of co-occurring medical and mental health conditions. The identification of more homogenous subgroups is likely to lead to a better understanding of etiologies as well as more targeted interventions and treatments. In 2006, we initiated the UC Davis MIND Institute Autism Phenome Project (APP) with the overarching goal of identifying clinically meaningful subtypes of autism. This ongoing longitudinal multidisciplinary study now includes over 400 children and involves comprehensive medical, behavioral, and neuroimaging assessments from early childhood through adolescence (2–19 years of age). We have employed several strategies to identify sub-populations within autistic individuals: subgrouping by neural, biological, behavioral or clinical characteristics as well as by developmental trajectories. In this Mini Review, we summarize findings to date from the APP cohort and describe progress made toward identifying meaningful subgroups of autism.

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Language Growth in Young Children with Autism: Interactions Between Language Production and Social Communication

Cited by 31 publications

References 136 publications

Electroencephalographic Abnormalities in Autism Spectrum Disorder: Characteristics and Therapeutic Implications

Electroencephalographic Abnormalities in Autism Spectrum Disorder: Characteristics and Therapeutic Implications

Lexical Semantic Knowledge of Children with ASD—a Review Study

The Autism Phenome Project: Toward Identifying Clinically Meaningful Subgroups of Autism

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