It is indisputable that COVID-19 virus interfered with the health status, education, socio economic impact on Sri Lanka and is threatening the entire world at present. Several vaccines are being developed; clinical trials are being performed aiming to eradicate the virus. The application of traditional medicinal plants as treatments of patients or as supportive therapies is a common topic being discussed today. In this review, we discuss the current situation of COVID-19 infection in Sri Lanka, pathogenesis of the entry of COVID-19 virus to human red blood cells, hematological complications, existing laboratory diagnosis methods. We discuss the properties of traditional Sri Lankan plant, Lantana camara and how its activities are useful to act against the fatal pathophysiology that may associate with COVID-19 infected and post COVID-19 infected blood. Furthermore, we create a platform to discuss the possibilities of using Lantana camara in the management of COVID-19 patients in future.