Laparoscopic Adrenalectomy in Children for Neuroblastoma

Barros, Fábio de; Romão, Rodrigo Luiz Pinto; Pinho-Apezzato, M.L.; Velhote, Manoel Carlos Prieto; Ricardi, Luiz Roberto Schlaich; Leal, Antonio José Gonçalves; Tannuri, Ana Cristina Aoun; Carvalho, B. Silva Peixoto de; Filho, Vicente Odone; Tannuri, Uenis

doi:10.1097/sle.0b013e318242e549

Cited by 15 publications

(9 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Several studies, from a case series to multicenter studies for adrenalectomy and a large number of nephrectomies that examined MIS have been published, showing that MIS can be safely performed for malignant tumors. [9,11,22]…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Pediatric minimally invasive surgery for malignant abdominal tumor

et al. 2019

View full text Add to dashboard Cite

This study examined the safety and usefulness of minimally invasive surgery (MIS) for malignant abdominal tumors in pediatric patients and analyzed the factors affecting the resection margin, operative time, and hospital stay of neuroblastoma (NBL) patients.We retrospectively reviewed data of pediatric patients who underwent MIS for malignant abdominal tumors from January 2011 to June 2017 at the Seoul National University Children's Hospital. Sex; age at operation; diagnosis; tumor location; operation-related data, such as operation time and transfusion; and follow-up data were reviewed. We divided patients into an excision group and a biopsy group. Detailed pathologic data were reviewed to analyze factors affecting the resection margin of NBL. Median value and range were calculated for all continuous variables. Mann–Whitney test and χ 2 test were used as appropriate. P values of <.05 were considered significant.Thirty-four pediatric patients were included; 21 were boys. The median age was 4 (0.2–18) years. The most common diagnosis was NBL (17 patients; 50.0%). Three patients each were diagnosed with lymphoma, solid pseudopapillary tumor of the pancreas, and teratoma. The median tumor size was 3.4 (0.5–10.2) cm. The median operation time was 108 (55–290) minutes, and the median hospital stay was 5 (2–11) days. The number of conversions to open surgery was 4. There were no postoperative complications or mortality. There were 18 patients in the excision group and 16 in the biopsy group. Diagnosis and the number of patients receiving preoperative chemotherapy differed between the 2 groups. R0 resection of NBL was significantly higher in patients with stage 1 disease and those aged >2 years. There were no clinical factors influencing operative time or hospital stay.MIS was feasible and safe in pediatric patients with malignant abdominal tumors. R0 resection of NBL was related to age and stage.

show abstract

Section: Discussionmentioning

confidence: 99%

“…Several studies have reported on MIS for malignant diseases. Successful resection of NBL in 7 patients was reported in 2012 [9] . A study detailing 9 cases of laparoscopic malignant tumor resection of pediatric malignancies was published, 2 of which underwent open conversion [10] .…”

Section: Introductionmentioning

confidence: 99%

Pediatric minimally invasive surgery for malignant abdominal tumor

et al. 2019

View full text Add to dashboard Cite

show abstract

“…Because of the adrenal neuroblastoma's characteristic is invasion growth, the majority of patients in need of open surgery. There are many authors believe that the intraperitoneal is the better surgical approach, and can simultaneously bilateral adrenal exploration areas, and major bleeding complications [14].…”

Section: Discussionmentioning

confidence: 99%

Pleura Metastasis from Adrenal Neuroblastoma

Guo¹,

Yang²,

H³

2016

Andrology (Los Angel)

View full text Add to dashboard Cite

“…Indeed, 52 of 119 publications were related to the paediatric age: Numerous of these reports have described successful laparoscopic removal of the adrenal gland in children, and it is actually an accepted procedure to treat children with adrenal tumours; however, most of these studies included retrospective cohort studies, only a few prospective cohort studies were performed, missing randomised controlled trials or controlled clinical trials and long-term follow-up, so the advantages and disadvantages of laparoscopic in paediatric abdominal neuroblastoma still need to be defined, and the role of MIS in paediatric cancer is a matter of debate, and its use is limited to lesions that are small, well-circumscribed, without local infiltration or metastasis. [ 5 ]…”

Section: Discussionmentioning

confidence: 99%

Laparoscopic treatment of adrenal masses in children: Report of two cases and review of literature

Orofino

Maggipinto

Lanzillotto

et al. 2016

Afr J Paediatr Surg

View full text Add to dashboard Cite

Laparoscopic adrenalectomy has become a common alternative to open surgery for the resection of adrenal lesions in adults: The advantages are to provide better exposure of the adrenal gland, diminish soft tissue dissection, decrease morbidity and postoperative pain; however, reporting on the laparoscopic adrenalectomy in paediatric patients has been limited. We present two cases of laparoscopic adrenalectomy performed at our institution in two children, for left adrenal neuroblastoma in a first patient with opsomyoclonus syndrome, and for a right incidentaloma in the second case. According to recent literature, our experience has demonstrated that the laparoscopic adrenalectomy is a feasible procedure in children with small, well-circumscribed adrenal masses: It can be used a safety to treat suspected benign and malignant adrenal masses in children, with minimal morbidity and short hospital stay. The lateral trans-peritoneal approach offers optimal visualisation and good outcomes in terms of minimal discomfort, rapid recovery and excellent cosmesis. However, in the paediatric field, the number of patients is limited, making the learning curve longer.

show abstract

Laparoscopic Adrenalectomy in Children for Neuroblastoma

Abstract: The laparoscopic approach for adrenal neuroblastoma resection is feasible in children with good outcomes, but should be reserved to patients with small, well-circumscribed adrenal lesions, without invasive or infiltrative disease.

Cited by 15 publications

References 16 publications

Pediatric minimally invasive surgery for malignant abdominal tumor

Pediatric minimally invasive surgery for malignant abdominal tumor

Pleura Metastasis from Adrenal Neuroblastoma

Laparoscopic treatment of adrenal masses in children: Report of two cases and review of literature

Contact Info

Product

Resources

About