Laparoscopic anatomical versus non-anatomical liver resection for hepatocellular carcinoma in the posterosuperior segments: a propensity score matched analysis

Abstract

Background: Since laparoscopic anatomical resection (LAR) for tumors, especially located in the posterosuperior (PS) segments of the liver remains difficult, laparoscopic non-anatomical resection (LNAR) are generally preferred. To compare the clinical outcomes between LAR and LNAR for hepatocellular carcinoma (HCC) located in the PS segments.Methods: We retrospectively reviewed the data for 1,029 patients who underwent hepatectomy for HCC between 2004 and 2018. Of 167 patients who underwent laparoscopic hepatectomy for HCC in PS segments, 64 underwent LNAR and 103 underwent LAR. Patient were matched one-to-one using propensity score matching (46:46).Results: LNAR was associated with significantly shorter operation time (P=0.001), lower estimated blood loss (P=0.001), lower transfusion rate (P=0.006) and shorter hospital stay (P=0.012) than LAR. The

Comment on ‘Effect of anatomical liver resection for hepatocellular carcinoma: a systematic review and meta-analysis’

“…Lee et al . 10 compared laparoscopic anatomical resection (LAR) with laparoscopic nonanatomical resection (LNAR) for posterior segment (PS) HCC using PSM and found that LNAR is a safe and feasible procedure with comparable oncological outcomes to LAR. Therefore, LNAR can be considered when the tumor is located in the PS and LAR cannot be performed.…”