HighlightsThere are several endoscopic, laparoscopic and open surgical procedures available for the management of GIST tumors near the GE junction.We present a case-report utilizing both endoscopy and laparoscopy to facilitate resection using the non-touch lesion-lifting technique.Pathology demonstrated a 4.7 cm GIST. The patient was discharged on post-operative day 3 with no complications.We include a full literature review and describe the various combined modalities available for successful resection.