Laparoscopic approach for T4 colon cancer can be associated with poor prognosis in right-sided T4b tumours

You, Kiho; Park, Hyoung-Chul; Park, Sung Chan; Sohn, Dae Kyung; Oh, Jae Hwan; Lee, Dongwon; Kang, Seung Joo; Heo, Seung Chul; Kim, Min Jung; Park, Kyu Joo

doi:10.1016/j.ejso.2021.01.009

Cited by 3 publications

(1 citation statement)

References 26 publications

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“…High-risk Stage II CRC is clearly associated with a poor prognosis; therefore, indications for perioperative treatments need to be more carefully considered during the COVID-19 pandemic than before. Furthermore, the oncological feasibility of the safety of MIS for T4 CRC cases, particularly T4b, remains controversial (23)(24)(25).…”

Section: Covid-19 Pandemic In Japan A) Covid-19 Cases Reported Monthl...mentioning

confidence: 99%

Minimally Invasive Surgery for Colorectal Cancer During the COVID-19 Pandemic in a Tertiary Medical Facility in Japan

Kudou

Yamauchi²,

Yamazato³

et al. 2022

In Vivo

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Background/Aim: The coronavirus disease 2019 pandemic has reduced hospital visits due to concerns regarding infection and also resulted in cancer screening delays. These changes may have had an impact on the progression of colorectal cancer (CRC). Therefore, the present study investigated the effects of the COVID-19 pandemic on minimally invasive surgery (MIS) for CRC using a correlation analysis of clinical outcomes before and during the COVID-19 pandemic. Patients and Methods: The present study targeted CRC patients who underwent MIS between

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Section: Covid-19 Pandemic In Japan A) Covid-19 Cases Reported Monthl...mentioning

confidence: 99%

Minimally Invasive Surgery for Colorectal Cancer During the COVID-19 Pandemic in a Tertiary Medical Facility in Japan

Kudou

Yamauchi²,

Yamazato³

et al. 2022

In Vivo

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Comparison of laparoscopic and open colectomy for splenic flexure colon cancer: a systematic review and meta-analysis

et al. 2022

Int J Colorectal Dis

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CD4 and FOXP3 as predictive markers for the recurrence of T3/T4a stage II colorectal cancer: applying a novel discrete Bayes decision rule

et al. 2022

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Background We recently reported the relapse-free survival (RFS) significance of the combination of CD4+ and forkhead box P3+ (FOXP3) T-cell densities identified by immunohistochemistry in patients with stage I, II, and III colorectal cancer (CRC) who underwent curative resections. This study was designed to determine the optimal combination of markers that predict recurrence in patients with T factors of T3/T4a stage II CRC by applying a novel Bayes decision rule. Methods Using 137 cancer tissue specimens from T3/T4a stage II patients, 12 clinicopathologic and immune factors were analysed as predictive candidates for recurrence. Results Our study showed that the combination of low CD4+ and low FOXP3+ T-cell densities resulted in extremely poor RFS. Conclusions Adjuvant chemotherapy may be considered for patients with a combination of low CD4+ and low FOXP3+ T-cell densities. The discovery of this new prognostic indicator is important for the appropriate management of patients undergoing curative resection for T3/T4a stage II CRC.

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Laparoscopic approach for T4 colon cancer can be associated with poor prognosis in right-sided T4b tumours

Cited by 3 publications

References 26 publications

Minimally Invasive Surgery for Colorectal Cancer During the COVID-19 Pandemic in a Tertiary Medical Facility in Japan

Minimally Invasive Surgery for Colorectal Cancer During the COVID-19 Pandemic in a Tertiary Medical Facility in Japan

Comparison of laparoscopic and open colectomy for splenic flexure colon cancer: a systematic review and meta-analysis

CD4 and FOXP3 as predictive markers for the recurrence of T3/T4a stage II colorectal cancer: applying a novel discrete Bayes decision rule

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