Laparoscopic Approach in Liver Harvesting from Living Donors for Transplantation in Children

Gautier, S. V.; Monakhov, Artem; Gallyamov, E. A.; Zagaynov, Evgeny; Цирульникова, О. М.; Semash, Konstantin; Dzhanbekov, Timur; Хизроев, Х. М.; Олешкевич, Д. О.; Chekletsova, E. V.

doi:10.16931/1995-5464.2018-1-13-18

Cited by 3 publications

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“…Before PSM, our results demonstrated that surgical treatment was the most significant protective factor of all clinical factors for OS and CSS, although a severe imbalance in the distribution of clinicopathological features between the surgery and non-surgery groups existed in our study. Whereas, the biases in data distribution in terms of baseline characteristics would interfere with the comparison between groups and the accuracy of the Cox regression model (34,35). To determine the benefits of surgery in older patients and reduce confounding factor interference between the surgery group and the nonsurgery group, we performed the 1:2 PSM to balance the distribution of a total of seven clinical characteristics so that the OS and CSS could be compared between the two groups at similar baselines and with a convincing result.…”

Section: Discussionmentioning

confidence: 99%

The role of surgery in older patients with T1-2N0M0 small cell lung cancer: A propensity score matching analysis

et al. 2022

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BackgroundSurgical resection could improve the survival of patients with early-stage small cell lung cancer (SCLC). However, there is a lack of dedicated studies concentrating on surgical treatment in older patients with T1-2N0M0 SCLC. Thus, we performed this population-based study to investigate whether older patients with T1-2N0M0 SCLC could benefit from surgery.MethodsWe collected the data of patients with SCLC between 2000 and 2015 from the Surveillance, Epidemiology, and End Results Program database. Older patients (≥ 65 years) with T1-2N0M0 SCLC were included, and we converted the staging information into those of the eighth edition. The propensity score matching (PSM) was used to balance the distribution of clinical characteristics between surgery and no-surgery groups.ResultsBefore PSM, the distribution proportions of clinical characteristics in 1,229 patients were unbalanced. The Kaplan–Meier curves of overall survival (OS) and cancer-specific survival (CSS) showed that the patients in the surgery group were better than those in the non-surgery group (all P < 0.001). After 1:2 PSM, the distribution proportions of clinical characteristics in 683 patients were balanced (all P > 0.05). The OS and CSS of patients in the surgery group were still better than that of patients in the no-surgery group (all P < 0.001), and subgroup analysis showed that the surgery was a protective factor for OS and CSS in all clinical characteristics subgroups (almost P < 0.001). The multivariate Cox analysis further confirmed this result (OS: HR, 0.33; 95% CI, 0.27–0.39; P < 0.001; CSS: HR, 0.29; 95% CI, 0.23–0.36; P < 0.001). The result of subgroup analysis based on age, T stage, and adjuvant therapy showed that surgery was related to better OS and CSS compared with non-surgery group (almost P < 0.001) and that lobectomy exhibited the longer survival than sublobectomy. Age, sex, and race were the independent prognostic factors for OS in patients undergoing surgery, whereas only the factor of age affects the CSS in patients with surgery.ConclusionsOlder patients with T1-2N0M0 SCLC can benefit significantly from surgical treatment, and lobectomy provides better prognosis than sublobectomy.

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Section: Discussionmentioning

confidence: 99%

The role of surgery in older patients with T1-2N0M0 small cell lung cancer: A propensity score matching analysis

et al. 2022

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“…Так, в родственной трансплантации печени широко используется лапароскопическое взятие трансплантатов печени. Были проанализированы данные, и показано, что техника изъятия трансплантата не влияет на частоту развития ранних артериальных осложнений [50][51][52][53].…”

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Vascular complications after liver transplantation: contemporary approaches to detection and treatment. A literature review

Semash,

Dzhanbekov,

Akbarov

2023

RJTAO

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Robotic surgery in the aspect of liver transplantation

Semash

2024

Transplantologiâ (Mosk.)

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Introduction. Almost 60 years have passed since the first liver transplant performed by Thomas Starzl. During this time, medical technologies have gradually improved, which has made it possible to use more and more new methods and approaches in this type of medical care. One of the new techniques of recent decades is robotic surgery, which is gradually being introduced into medical practice, including in the field of transplant medicine.Objective. The purpose of writing this review was to summarize knowledge and describe the current status of development of robotic surgery in the aspect of liver transplantation, namely: liver resection in donors, as well as graft implantation in the recipient.Material and methods. The review includes foreign and domestic publications on minimally invasive donor liver surgery. Publications on the topic of robotic liver resection in the aspect of liver transplantation were also processed.Conclusion. Robotic surgery using advanced robotic systems represents the next step in the development of minimally invasive technologies in liver transplantation. Robotic systems provide more precise and dexterous control of instruments, allowing surgeons to perform complex procedures with greater precision and less risk to patients. However, the robotic approach is still very limited in geographical distribution and requires much more experience than laparoscopy. The upcoming introduction of new robotic systems that support haptic feedback or cavitronic ultrasonic surgical aspirators will further promote a widespread adoption of robotic liver resection in liver donors and liver recipients.

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Laparoscopic Approach in Liver Harvesting from Living Donors for Transplantation in Children

Cited by 3 publications

References 0 publications

The role of surgery in older patients with T1-2N0M0 small cell lung cancer: A propensity score matching analysis

The role of surgery in older patients with T1-2N0M0 small cell lung cancer: A propensity score matching analysis

Vascular complications after liver transplantation: contemporary approaches to detection and treatment. A literature review

Robotic surgery in the aspect of liver transplantation

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