Laparoscopic-assisted vaginal radical hysterectomy (LAVRH) in recipients of kidney transplant with cervical cancer stage Ib1

Abstract

The incidence of cancer among patients submitted to kidney transplantation is increasing, since the graft survival rates have improved. Cervical cancer is approximately fivefold more common among these patients, correlated to immunosuppression exposure and antibody response to HPV infection. Treatment is challenging, regarding the graft in the pelvic field and standard options for stage Ib include radical hysterectomy or chemoradiation. We report two patients submitted to kidney transplantation with cervical cancer that were successfully treated by means of surgery. In conclusion, we intended to enlarge the current experience with radical hysterectomy in transplanted kidney patients with early stage cervical cancer. Although surgical difficulties existed, we could attest the feasibility and oncologic safety of the method.