Laparoscopic cholecystectomy and time-course changes in renal function

Abstract

Our findings demonstrate that reduction of IAP to 4 mmHg using the retraction method prevents the transient renal dysfunction caused by prolonged 12 mmHg pneumoperitoneum during LC, suggesting that the retraction method reduces the risk of perioperative renal dysfunction during laparoscopic surgery.

Renal hemodynamics during carbon dioxide pneumoperitoneum

“…Only a few studies of renal function at 12 mmHg or less of CO 2 PP have been published. Various species, pressure levels of PP, and procedures have been studied, and the results generally show a decrease in renal function and an increase in vasopressin levels [5,8,9,10,16,17]. Interestingly, one study showed that a vasopressin antagonist decreased the renal effects [1].…”

The influence of periarterial papaverine application on intraoperative renal function and blood flow during laparoscopic donor nephrectomy in a pig model

“…However, there is compelling evidence that the pneumoperitoneum reduces renal blood flow [3,9,10,18]. In addition, compared with open surgery, endoscopic dissection techniques require longer surgical manipulation in the vicinity of the renal artery, potentially causing arteriospasm.…”

Impact of Pneumoperitoneum on the Post-Operative Renal Function and Level of Acute Kidney Injury Markers: Comparison between Laparoscopic and Open Nephrectomy

“…In a review of five animal studies, Shafer, et al demonstrated a decrease in renal perfusion ranged from 12% to 14% [14]. Miki, et al reported a decreased urine output and GFR in patients after laparoscopic cholecystectomy, whereas no significant changes in these parameters were observed when an abdominal lift device was used [15].…”