“…Modern surgical series in which extended cholecystectomy was carried out, mainly from Asia, reported better survival [4][5][6][7][8][9]. In patients with tumour limited to the mucosa, in which the risk of lymph node involvement is about 2.5%, simple cholecystectomy should be enough, even when a laparoscopic approach is used [10][11][12][13][14][15]. However, the risk of lymph node involvement when the tumour invades the muscle rises to 15%, which in our opinion should require more than a simple cholecystectomy, meaning extended cholecystectomy, usually through a second surgical procedure and adjuvant radio-chemotherapy (RT-CT).…”