Laparoscopic Nissen fundoplication mainly reduces the volume of acid reflux and potentially improves mucosal integrity up to the middle esophagus in neurologically impaired children detected by esophageal combined pH–multichannel intraluminal impedance measurements

Fukahori, Suguru; Yagi, Minoru; Ishii, Shinji; Asagiri, Kimio; Saikusa, Nobuyuki; Hashizume, Naoki; Yoshida, Misao; Masui, Daisuke; Sakamoto, Saki; Tsuruhisa, Shihori; Kurahachi, Tomohiro; Tanaka, Yoshiaki

doi:10.1016/j.jpedsurg.2016.01.012

Cited by 16 publications

(7 citation statements)

References 24 publications

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“…In the present study, long‐term vomiting was only noted in 2.4% of patients. Previously, based on MII‐pH measurements, we reported that VAG and Nissen fundoplication mainly reduced the volume of acid reflux and might improve mucosal integrity up to the middle of the esophagus in children with NI 16 . This result supported the notion that MII‐pH measurements and Nissen fundoplication are associated with a reduced risk of long‐term vomiting.…”

Section: Discussionsupporting

confidence: 76%

Complications in patients with neurological impairment after gastrostomy

Sakamoto

Hashizume

Fukahori

et al. 2021

Pediatrics International

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Background Neurological impairment (NI) is responsible for most conditions that require a permanent gastrostomy tube. The present study assessed the occurrence of short‐ and long‐term complications after video‐assisted gastrostomy (VAG) in patients with NI. Methods The incidence of short‐ (<6 months) and long‐term (over 2 years) complications of VAG were analyzed in a retrospective study. The differences between the incidence of the complications of VAG according to the age at surgery (≤15 years vs. ≥16 years) were also evaluated. The short‐ and long‐term complications observed were granulation tissue formation, infection requiring antibiotic treatment, skin problems, perigastrostomy leakage, vomiting, accidental tube dislodgement, dumping syndrome, ileus, and peritonitis. Results Eighty‐two patients were evaluated for short‐ and long‐term complications. The long‐term complication rate was significantly lower than the short‐term complication rate (P = 0.0026). Onodera’s prognostic nutritional index before VAG in patients with long‐term complications was significantly lower than in patients without such complications (P = 0.046). The incidence of long‐term granulation tissue formation, infection, and vomiting were significantly lower than those of similar short‐term complications. Long‐term skin problems were associated with short‐term skin problems (odds ratio: 18.95; 95% confidence interval: 4.53–92.98; P < 0.001). The number of patients ≥16 years old with short‐ and long‐term skin problems was significantly higher than in patients ≤15 years old (P = 0.0014 and P = 0.0073, respectively). Conclusions The incidence rate of granulation tissue formation and infection after VAG were lower in the long term than in the short term. However, patients ≥16 years old presented with persistent complications.

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Section: Discussionsupporting

confidence: 76%

Complications in patients with neurological impairment after gastrostomy

Sakamoto

Hashizume

Fukahori

et al. 2021

Pediatrics International

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“…24-hour pH monitoring performed before and after LNF in a study of 127 children found that median RI changed from 10 % preoperatively to 0.5 % in patients with NI and to 0.8 % in patients without NI after 3 months (149). A reduced number of acidic and non-acidic episodes have also been found (150). In forty patients undergoing an UGI contrast study 6 months after fundoplication, 87 % were without signs of GER or a herniated wrap (151).…”

Section: Symptom Improvement and Objective Measuresmentioning

confidence: 97%

Trends in the use of gastrostomies at a tertiary paediatric referral centre

Kvello

Åvitsland

Knatten

et al. 2015

Scandinavian Journal of Gastroenterology

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“…13,15 We also recently demonstrated that the BI value increased after laparoscopic Nissen fundoplication in NI children suffering from GERD. 16 However, as mentioned above, although several studies have evaluated the BI, to the best of our knowledge, no studies thus far referred to the role of BI in NI patients.…”

Section: Multichannel Intraluminal Impedance Ph Measurements (Ph/mii)mentioning

confidence: 99%