2017
DOI: 10.1097/md.0000000000008085
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Laparoscopic Nissen (total) versus anterior 180° fundoplication for gastro-esophageal reflux disease

Abstract: Background:Laparoscopic Nissen fundoplication (LNF) has been the gold standard for the surgical management of Gastro-esophageal reflux disease (GERD). Laparoscopic anterior 180° fundoplication (180° LAF) is reported to reduce the incidence of postoperative complications while obtaining similar control of reflux. The present meta-analysis was conducted to confirm the value of the 2 techniques.Methods:PubMed, Medline, Embase, Cochrane Library, Springerlink, and China National Knowledge Infrastructure Platform da… Show more

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Cited by 43 publications
(28 citation statements)
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“…37 Other studies have found similar results. 38,39 In the context of primary RYGB, two studies have indicated that the percentage of patients on PPIs does not change and may even increase after surgery. 40,41 Although the percentage of patients in our study who remained on acidsuppressing medication is higher than that in the aforementioned studies (particularly those assessing primary RYGB), this may be explained by the fact that outcomes of antireflux operations are worse after reoperations than after primary operations.…”
Section: Discussionmentioning
confidence: 99%
“…37 Other studies have found similar results. 38,39 In the context of primary RYGB, two studies have indicated that the percentage of patients on PPIs does not change and may even increase after surgery. 40,41 Although the percentage of patients in our study who remained on acidsuppressing medication is higher than that in the aforementioned studies (particularly those assessing primary RYGB), this may be explained by the fact that outcomes of antireflux operations are worse after reoperations than after primary operations.…”
Section: Discussionmentioning
confidence: 99%
“…The evidence suggests that there is little difference in post-operative dysphagia when comparing full and partial posterior fundoplication[20] and while the evidence from the randomized trials comparing posterior with anterior fundoplication was mixed. A recent meta-analysis has reported that both anterior and posterior fundoplication are equally effective at controlling reflux symptoms the 180 0 anterior fundoplication is associated with a lower incidence of post-operative dysphagia[21]. As a consequence an anterior fundoplication is associated with fewer re-operations (carried out for dysphagia).…”
Section: Comparison Between Full and Partial Wrapsmentioning
confidence: 99%
“…180°l aparoscopic anterior fundoplication can reduce the incidence of postoperative dysphagia while this is offset by a higher risk of reoperation for recurrent symptoms. The risk of recurrent symptoms should need to be balanced against the risk of dysphagia when surgeons choose surgical procedures for each individual with GERD [16]. More studies have shown that at 1 and 5 years post-surgery, dysphagia and gas-related symptoms are lower after 180°l aparoscopic anterior fundoplication than after laparoscopic Nissen's fundoplication, and esophageal acid exposure and esophagitis are similar, with no differences in heartburn scores, patient satisfaction, dilatations, and reoperation rate.…”
Section: Introductionmentioning
confidence: 99%