Laparoscopic Resection of Schwannoma of the Ascending Colon

Tashiro, Yoshihiko; Matsumoto, Fumio; Iwama, Keiko; Shimazu, Ai; Matsumori, Sei; Nohara, Shigeo; Miura, Hiroyoshi; Takei, Masahiko; Namekata, Koji; Takase, Masaru; Okada, Motoi; Tsumura, Hidenori

doi:10.1159/000373882

Cited by 35 publications

(8 citation statements)

References 14 publications

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“…For differential diagnosis of schwannoma, abdominal CT scan can help differentiate between schwannoma and other mesenchymal tumors. Schwannomas appear as well-defined homogenous mural masses with low enhancement [ 1 , 5 , 7 , 10 , 11 , 14 , 35 , 36 , 40 , 51 , 70 ] in comparison with the heterogenous aspect of GIST and the ill-defined aspect of adenocarcinomas [ 72 ]. Less than half of the published case reports had a CT scan done, approximately half of these had endoluminal resection and did not require abdominal imaging.…”

Section: Discussionmentioning

confidence: 99%

Schwannoma of the colon and rectum: a systematic literature review

et al. 2018

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BackgroundSchwannomas of the colon and rectum are rare among gastrointestinal schwannomas. They are usually discovered incidentally as a submucosal mass on routine colonoscopy and diagnosed on pathologic examination of the operative specimen. Little information exists on the diagnosis and management of this rare entity.The aim of this study is to report a case of cecal schwannoma and the results of a systematic review of colorectal schwannoma in the literature.Main bodyPubMed, Scopus, and Cochrane database searches were performed for case reports and case series of colonic and rectal schwannoma.Ninety-five patients with colonic or rectal schwannoma from 70 articles were included. Median age was 61.5 years (59% female). Presentation was asymptomatic (28%), rectorrhagia (23.2%), or abdominal pain (15.8%). Schwannoma occurred in the left and sigmoid colon in 36.8%, in the cecum and right colon in 30.5%, and in the rectum in 21.1%. Median tumor size was 3 cm and 56.2% of patients who underwent preoperative colonoscopy had a typical smooth submucosal mass. At pathology, 97.9, 13.7, and 5.3% of schwannomas stained positive for S100, vimentin, and GFAP, respectively. The median mitotic index was 1/50.ConclusionsColorectal schwannoma is a very rare subtype of gastrointestinal schwannoma which occurs in the elderly, almost equally in men and women. Schwannoma should be included in the differential diagnosis of a submucosal lesion along with gastrointestinal stromal tumor, neuro-endocrine tumors, and leiomyoma-leiomyosarcoma. Definitive diagnosis is based on immunohistochemistry of the operative specimen. Rarely malignant, surgery is the mainstay of treatment.

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Section: Discussionmentioning

confidence: 99%

Schwannoma of the colon and rectum: a systematic literature review

et al. 2018

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“…Schwannoma can occur at any location throughout the body along the peripheral nerves [ 1 , 12 ]. Gastrointestinal schwannoma most commonly originates in the Auerbach's nerve plexus and, at times, in the Meissner's nerve plexus [ 3 , 13 ].…”

Section: Discussionmentioning

confidence: 99%

“…Gastrointestinal schwannoma assumes the form of a submucosal tumor. The incidence of schwannoma has been reported to be 2%–6% of all submucosal tumors of the intestine [ 12 , 14 ]. In the primary gastrointestinal submucosal tumor, GIST and NET G1 may be malignant; therefore, preoperative diagnosis of gastrointestinal submucosal tumors is considered important although this is challenging as these tumors are often confused with other neoplasms despite advances in the imaging studies [ 2 ].…”

Section: Discussionmentioning

confidence: 99%

Laparoscopic Resection of Appendiceal Schwannoma

Imagami

Takayama

Maeda

et al. 2018

Case Reports in Surgery

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Background Schwannoma arises from Schwann's cell of the neural sheath. Schwannoma of the large intestine, particularly of the appendix, is rare. We report a case of appendiceal schwannoma resected using laparoscopic surgery. Case Presentation A 75-year-old man was referred to our hospital for abdominal fullness and nausea since 2 months. Abdominal CT revealed a well-demarcated oval mass of 25 mm at the tip of the appendix. Contrast-enhanced CT revealed a lesion with gradually enhanced contrast from the arterial phase to the equilibrium phase. Abdominal US revealed a well-demarcated hypoechoic tumor. Preoperative diagnosis indicated appendiceal mesenchymal or neuroendocrine tumor. Ileocecal resection with D3 lymph node dissection was performed. Pathological and immunohistochemical findings confirmed the diagnosis of appendiceal schwannoma. Conclusions For determining the surgical procedure of nonepithelial tumor of the appendix, preoperative diagnosis of mesenchymal or neuroendocrine tumors is required. However, appendiceal schwannoma is extremely rare, and its characteristic findings have not yet been established. Accumulating cases of appendiceal schwannomas is necessary for improving imaging diagnosis and surgical treatment.

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“…They most frequently affect the stomach (83%) and small intestine (12%), whereas primary schwannoma of the colon unassociated with systemic neurofibromatosis is extremely rare. 2,3 Usually, schwannomas tend to be an incidental finding, with rectal bleeding or obstructive symptoms being reported very rarely. 4 Their diagnosis is based largely on surgically resected specimens.…”

Section: Discussionmentioning

confidence: 99%