Laparoscopic Roux-en-Y Gastric Bypass and Its Early Effect on Blood Pressure

Ahmed, Ahmed R.; Rickards, Gretchen; Coniglio, Deb; Xia, Yinglin; Johnson, Joseph; Boss, Thad; O’Malley, William

doi:10.1007/s11695-008-9671-z

Cited by 94 publications

(64 citation statements)

References 27 publications

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“…Table 1 shows the basic characteristics of these 9 studies. These included one randomized controlled trial, one control clinical trial, one retrospective study, and six prospective studies [17][18][19][20][21][22][23][24][25]. The nine studies involved a total of 2756 patients (3 studies were from Sweden, 2 from United States of America, and one each from United Kingdom, Norway, China, and Denmark).…”

Section: Resultsmentioning

confidence: 99%

“…Ahmed et al [20], showed that hypertension remission rate was 66% in a Prospective study on 100 patients, suggesting a hormonal mechanism maybe involved for the changes observed, various neuroendocrine changes have been postulated to play a role in this. The gut peptide glucagon-like peptide 1 (GLP-1) has been implicated by some in the early improvement in glycemic control after LRYGBP [26].…”

Section: Discussionmentioning

confidence: 95%

“…Weight loss will therefore eliminate the adipose tissue related causes of hypertension. Sjöström et al [17] 2 Years VBG/LRGBP 28±15 kg 7±18 6±11 Sjöström et al [18] 8 Years VBG/GB/LRGBP 20±15.7 kg 2.9±22 1.9±14 Sjöström et al [19] 8 Years VBG/GB/LRGBP 33.8±18.1 kg −20 −11 Ahmed et al [20] 1 Year LRGBP 45 kg −15 −9 Nordstrand et al [21] 1 Year LRGBP 41 kg −23 −13 Fenske et al [22] 1 Year LRGBP/GB/LSG 45 kg 18±1.6 12±1.0 Liang et al [23] 1 Year LRGBP 24% 34±4.9 −10 Dogan et al [24] 8 Years LRGBP 39.4±17.1 28% reduction 28% reduction Bonfils et al [25] 1 Year LRGBP 38.5±21. This short review will deal with the impact of metabolic and bariatric surgery on hypertension incorporated with evaluating published data.…”

Section: Introductionmentioning

confidence: 99%

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Effect of Bariatric Surgery on Hypertension

Alhomound

2015

J Metab Bariatr Surg

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High blood pressure is a serious health problem and a primary risk factor for both stroke and heart disease. Many studies have strongly assessed short-term effects as well as long-term effects of bariatric surgery on type2 diabetes mellitus, whereas little attention has been paid to the effect on hypertension. This review study was designed to evaluate the impact of Bariatric Surgery and weight loss on obese patients with hypertension, and whether the hypertension improved or resolved post-surgery. Relevant papers were searched using MEDLINE, Science Citation Index, Pub Med, and Clinical Evidence, by using the searched terms (Hypertension, Bariatric, Obesity, and Surgery). The association between weight reduction and Hypertension control is hard to analyze. And well-organized studies with a long term follow up are required to determine the effect of Bariatric Surgery and Hypertension control.

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Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 95%

Section: Introductionmentioning

confidence: 99%

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Effect of Bariatric Surgery on Hypertension

Alhomound

2015

J Metab Bariatr Surg

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“…The benefits of bariatric surgery, with improvement in parameters of the metabolic syndrome, have been long the object of study by several authors (1,2,6,12,42) . Few studies have aimed to observe the differences between genders and age groups after bariatric surgery.…”

Section: Discussionmentioning

confidence: 99%

AGE AND GENDER MAY INFLUENCE THE RESULTS OF ROUX-EN-Y GASTRIC BYPASS? Metabolic syndrome parameters

Andrade-Silva

Caranti

Sallet³

et al. 2014

Arq. Gastroenterol.

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-Context -Severe obesity affects the body favoring the development of serious diseases, including hypertension, diabetes mellitus, atherosclerosis and non alcoholic fatty liver disease. Bariatric procedures increased in Brazil in the last decade. Objectives -The purpose of this study was to verify if gender and age in date of procedure resulted significant differences in metabolic syndrome parameters after surgery. Methods -The study involved 205 medical records of adult patients undergoing Roux-en-Y gastric bypass, stratified by gender and age groups and followed one year by a multidisciplinary team. Results -It was observed significant decrease in body mass index, fasting glucose and insulin at all ages and both genders. Lipid profile showed significant improvements except high density lipoprotein cholesterol. Ectopic fat in the liver has decreased after 6 months in patients classified with steatosis at baseline. Patients classified as hypertensive blood pressure levels decreased 6 months after surgical intervention. Conclusion -Roux-en-Y gastric bypass proved to be an important tool in remission of metabolic syndrome parameters. The reduction of body mass accompanied to decrease in insulin resistance resulted in lower prevalence of comorbidities associated with obesity. The benefits were similar and extended both genders and all age groups between 18 and 65 years old. HEADINGS -Bariatric surgery. Metabolic syndrome X. Roux-en-Y anastomosis. Fatty liver.

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“…The reduction in blood pressure can be seen as early as 1 week postoperative [118]. Antihypertensive medications should be adjusted and patients' blood pressure should be monitored periodically.…”

Section: Medical Management Of Comorbidities and Medication Adjustmentmentioning

confidence: 99%